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Browse Mutations gyrAA74V

GenegyrA

Protein ChangeA74V

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: resistance
Resistance To: Fluoroquinolones
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Anti-Mycobacterial Activity of Bacterial Topoisomerase Inhibitors with Dioxygenated Linkers.

PMID 39792935 · 2025

Resistance mutations identified in gyrA gene of M. tuberculosis.

Mutation Information

Protein Change: A74V
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Fluoroquinolones

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

resistance

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Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research