ResLit - Antimicrobial Resistance Gene & Mutation Database

Nucleotide ChangeA1304T

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseResFinder DatabaseReslit

Overview

Resistance To: rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Evaluation of genotype MTBDRplus assay for rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis clinical isolates from Pakistan.

Research Article

PMID 28043516 · 2016

Mutation Information

rpoB: c.A1304T

Nucleotide Change: A1304T
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Validation Method: GenoType MTBDRplus assay
Source Database: Reslit

Compensatory mutations are associated with increased in vitro growth in resistant clinical samples of Mycobacterium tuberculosis.

Research Article

PMID 38315172 · 2024

mutations associated with rifampicin resistance

Mutation Information

rpoB: p.D435V / c.A1304T

Protein Change: D435V
Nucleotide Change: A1304T
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Validation Method: statistical association testing
Source Database: Reslit

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