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Browse Mutations gyrAY77S

GenegyrA

Protein ChangeY77S

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA gyrase subunit A GyrA
Resistance To: ciprofloxacin, quinolones
Organisms: Burkholderia pseudomallei
Papers: 1

Paper Information1

1

Within-Host Evolution of Burkholderia pseudomallei during Chronic Infection of Seven Australasian Cystic Fibrosis Patients.

Research Article

PMID 28400528 · 2017

GyrA Y77S mutation contributes to ciprofloxacin resistance.

gyrA

Mutation Information

Protein Change: Y77S
Organisms: Burkholderia pseudomallei
Confers Resistance To: ciprofloxacinquinolones
Effect on Function: DNA gyrase subunit A GyrA
Validation Method: genomic analysis and MIC testing
Source Database: ReslitReference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
GitHub
Zenodo archive
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research