Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
Review
Mutations in the rpoB gene are associated with rifampicin resistance in Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium kansasii.
Novel rapid PCR for the detection of Ile491Phe rpoB mutation of Mycobacterium tuberculosis, a rifampicin-resistance-conferring mutation undetected by commercial assays.
Research Article
Prediction of rifampicin resistance beyond the RRDR using structure-based machine learning approaches.
Research Article
The mutation I491F was identified as a low confidence mutation in the Miotto et al. study, showing weak clinical resistance evidence.
Compensatory effects of M. tuberculosis rpoB mutations outside the rifampicin resistance-determining region.
Research Article
Mutations P45L, P45S, I480V, V534M, and R827L are compensatory mutations that improve the fitness of the S450L mutant.
Drug-Resistant Characteristics, Genetic Diversity, and Transmission Dynamics of Rifampicin-Resistant Mycobacterium tuberculosis in Hunan, China, Revealed by Whole-Genome Sequencing.
Research Article
Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkers.
Research Article
Beyond Hotspot Mutations: Diagnostic Relevance of High Frequency, Low Frequency, and Disputed rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis.
Review
Mutations in rpoB are responsible for rifampicin resistance in Mycobacterium tuberculosis.
Thin-Layer-Agar-Based Direct Phenotypic Drug Susceptibility Testing on Sputum in Eswatini Rapidly Detects Mycobacterium tuberculosis Growth and Rifampicin Resistance Otherwise Missed by WHO-Endorsed Diagnostic Tests.
Research Article
Detected in 8/28 (28.6%) of confirmed RR isolates
A modified decision tree approach to improve the prediction and mutation discovery for drug resistance in Mycobacterium tuberculosis.
Research Article
Efflux pumps positively contribute to rifampin resistance in rpoB mutant Mycobacterium tuberculosis.
Research Article
Mutations in rpoB gene were associated with increased rifampin resistance.
Prospective Comparative Evaluation of the Xpert MTB/RIF and Xpert MTB/RIF Ultra Assays for Detecting Mycobacterium tuberculosis and Rifampin Resistance in High-resource, Intermediate-burden Settings.
Research Article
Rarity of rpoB Mutations Outside the Rifampicin Resistance-Determining Region of Mycobacterium tuberculosis Isolates from Patients Responding Poorly to First-Line Tuberculosis Regimens in Beijing, China: A Retrospective Study.
Research Article
Whole genomic analysis uncovers high genetic diversity of rifampicin-resistant Mycobacterium tuberculosis strains in Botswana.
Research Article
Rapid, accurate, and reproducible de novo prediction of resistance to antituberculars.
Research Article
Mutations in rpoB gene associated with rifampicin resistance
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance.
Research Article
Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance.
Research Article
Disputed mutation
Mycobacterium tuberculosis Drug Resistance and Transmission among Human Immunodeficiency Virus-Infected Patients in Ho Chi Minh City, Vietnam.
Research Article
Cryptic Resistance Mutations Associated With Misdiagnoses of Multidrug-Resistant Tuberculosis.
Research Article
noncanonical RIF resistance mutation
Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach.
Research Article
Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique.
Research Article
Role of the first WHO mutation catalogue in the diagnosis of antibiotic resistance in Mycobacterium tuberculosis in the Valencia Region, Spain: a retrospective genomic analysis.
Research Article
mutations in rpoB are associated with rifampicin resistance
Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis.
Review
Tuberculosis drug resistance mutation database.
Research Article
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics.
Research Article
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution?
Research Article
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
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