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Browse Mutations rpoBS490L

GenerpoB

Protein ChangeS490L

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: The S490L mutation in rpoB confers rifampicin resistance in B. velezensis.
Resistance To: rifampicin
Organisms: Bacillus velezensis
Papers: 1

Paper Information1

1

Rifampicin-Resistance Mutations in the rpoB Gene in Bacillus velezensis CC09 have Pleiotropic Effects.

Research Article

PMID 28243227 · 2017

Mutations in rpoB confer rifampicin resistance in B. velezensis.

Mutation Information

Protein Change: S490L
Organisms: Bacillus velezensis
Confers Resistance To: rifampicin
Effect on Function: The S490L mutation in rpoB confers rifampicin resistance in B. velezensis.
Validation Method: cloning in B. velezensis and MIC measurement; MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
GitHub
Zenodo archive
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research