ResLit - Antimicrobial Resistance Gene & Mutation Database

GenegrlA

Protein ChangeS80R

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA topoisomerase GrlA
Resistance To: enrofloxacin, fluoroquinolones, quinolones
Organisms: Staphylococcus coagulans, Staphylococcus pseudintermedius, Staphylococcus intermedius
Papers: 3

Paper Information3

Phenotypic and Molecular Traits of Staphylococcus coagulans Associated with Canine Skin Infections in Portugal.

Research Article

PMID 34063179 · 2021

Mutation Information

grlA: p.S80R

Protein Change: S80R
Organisms: Staphylococcus coagulans
Confers Resistance To: enrofloxacin
Validation Method: sequencing
Source Database: Reslit

Investigation of In Vitro Susceptibility and Resistance Mechanisms in Skin Pathogens: Perspectives for Fluoroquinolone Therapy in Canine Pyoderma.

Research Article

PMID 36139982 · 2022

Mutation Information

grlA: p.S80R

Protein Change: S80R
Organisms: Staphylococcus pseudintermedius
Confers Resistance To: fluoroquinolones
Validation Method: sequencing
Source Database: Reslit

Characterization of new staphylococcal cassette chromosome mec (SCCmec) and topoisomerase genes in fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius.

Research Article

PMID 18305127 · 2008

grlA

Mutation Information

grlA: p.S80R

Protein Change: S80R
Organisms: Staphylococcus intermedius
Confers Resistance To: quinolones
Effect on Function: DNA topoisomerase GrlA
Source Database: Reference Gene Catalog

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