ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp3

penicillin-binding protein

Protein ChangeP527S

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: reduced aztreonam binding
Resistance To: Aztreonam
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Tracing the evolutionary trajectory of the IncP-2 plasmid co-harboring bla (IMP-45) and bla (VIM-1): an outbreak of Pseudomonas aeruginosa co-producing IMP-45 and VIM-1 carbapenemases in China.

PMID 40612392 · 2025

associated with aztreonam resistance

Mutation Information

pbp3: p.P527S

Protein Change: P527S
Organisms: Pseudomonas aeruginosa
Confers Resistance To

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Mutation Information