ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeA139P

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReslit

Overview

Mechanism: single resistance variant
Resistance To: isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Prevalence and Molecular Characteristics Based on Whole Genome Sequencing of Mycobacterium tuberculosis Resistant to Four Anti-Tuberculosis Drugs from Southern Xinjiang, China.

Research Article

PMID 34466004 · 2021

Mutations in the katG gene are associated with isoniazid resistance.

Mutation Information

katG: p.A139P

Protein Change: A139P
Organisms: Mycobacterium tuberculosis
Confers Resistance To: isoniazid
Validation Method: whole genome sequencing
Source Database: Reslit

Novel katG mutations causing isoniazid resistance in clinical M. tuberculosis isolates.

Research Article

PMID 26251830 · 2015

Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid; CARD accession: CARD:3003392

Mutation Information

katG: p.A139P

Protein Change: A139P
Organisms: Mycobacterium tuberculosis
Confers Resistance To: isoniazid
Effect on Function: single resistance variant
Source Database: Card Database

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