Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Whole-genome recombination and dynamic accessory genomes drive the phenotypic diversity of Mycobacterium abscessus subspecies.
Strains with T28C mutation showed macrolide susceptibility, while wild-type erm41 gene showed inducible resistance.
Infection model of THP-1 cells, growth dynamics, and antimicrobial susceptibility of clinical Mycobacterium abscessus isolates from cystic fibrosis patients: Results from a multicentre study.
Evaluation of mlstverse system for accurate subspecies identification and drug resistance prediction in Mycobacterium abscessus species.
Time-to-Detection of Inducible Macrolide Resistance in Mycobacterium abscessus Subspecies and Its Association with the Erm(41) Sequevar.
The T28C mutation in the erm(41) gene renders the enzyme non-functional and does not result in inducible macrolide resistance.
Vancomycin and Clarithromycin Show Synergy against Mycobacterium abscessus In Vitro.
The C28 erm(41) sequevar is nonfunctional and hence susceptible to clarithromycin.
Subspecies distribution and drug-resistance characteristics of Mycobacterium abscessus complex clinical isolates in South China.
Dissecting erm(41)-Mediated Macrolide-Inducible Resistance in Mycobacterium abscessus.
T28C polymorphism is associated with loss of methylase activity and abrogation of inducible resistance
Whole-Genome Sequencing for Predicting Clarithromycin Resistance in Mycobacterium abscessus.
Analysis of drug-susceptibility patterns and gene sequences associated with clarithromycin and amikacin resistance in serial Mycobacterium abscessus isolates from clinical specimens from Northeast Thailand.
Subspecies Distribution and Antimicrobial Susceptibility Testing of Mycobacterium abscessus Clinical Isolates in Madrid, Spain: a Retrospective Multicenter Study.
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