Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Peruvian and globally reported amino acid substitutions on the Mycobacterium tuberculosis pyrazinamidase suggest a conserved pattern of mutations associated to pyrazinamide resistance.
Research Article
All mutations are missense mutations in the pncA gene associated with pyrazinamide resistance.
Effect of pyrazinamidase activity on pyrazinamide resistance in Mycobacterium tuberculosis.
Research Article
Mutations in pncA lead to decreased pyrazinamidase activity, contributing to pyrazinamide resistance.
Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets.
Research Article
Whole genome sequencing of clinical samples reveals extensively drug resistant tuberculosis (XDR TB) strains from the Beijing lineage in Nigeria, West Africa.
Research Article
A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance.
Research Article
Mutations in pncA are associated with pyrazinamide resistance.
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics.
Research Article
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
No comments yet. Be the first to comment!