Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
pncA Mutations as a Major Mechanism of Pyrazinamide Resistance in Mycobacterium tuberculosis: Spread of a Monoresistant Strain in Quebec, Canada.
Research Article
The study confirms that pncA mutations are the major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis.
Peruvian and globally reported amino acid substitutions on the Mycobacterium tuberculosis pyrazinamidase suggest a conserved pattern of mutations associated to pyrazinamide resistance.
Research Article
All mutations are missense mutations in the pncA gene associated with pyrazinamide resistance.
Whole genome sequencing-based detection of extensively drug-resistant tuberculosis from Ethiopia.
Research Article
Detection of multidrug resistance in Mycobacterium tuberculosis.
Research Article
mutations in pncA are associated with pyrazinamide resistance
Effect of pyrazinamidase activity on pyrazinamide resistance in Mycobacterium tuberculosis.
Research Article
Mutations in pncA lead to decreased pyrazinamidase activity, contributing to pyrazinamide resistance.
Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets.
Research Article
Phenotypic and genotypic characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates in Zhejiang, China.
Research Article
Mycobacterium tuberculosis whole genome sequencing provides insights into the Manila strain and drug-resistance mutations in the Philippines.
Research Article
Confirmed in the study
A retrospective genomic analysis of drug-resistant strains of M. tuberculosis in a high-burden setting, with an emphasis on comparative diagnostics and reactivation and reinfection status.
Research Article
Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan.
Research Article
Mutations in the pncA gene were identified in PZA-resistant isolates.
A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance.
Research Article
Mutations in pncA are associated with pyrazinamide resistance.
Detection of drug resistant Mycobacterium tuberculosis by high-throughput sequencing of DNA isolated from acid fast bacilli smears.
Research Article
Mutations in pncA are associated with pyrazinamide resistance.
Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis.
Research Article
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.
Research Article
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics.
Research Article
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
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