Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis.
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all mutations are in the rpoB gene and confer resistance to rifampin
Genetic determinants of drug-resistant tuberculosis among HIV-infected patients in Nigeria.
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Rifabutin Resistance Associated with Double Mutations in rpoB Gene in Mycobacterium tuberculosis Isolates.
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Mutations in rpoB gene are associated with rifabutin resistance
Rapid detection of rpoB gene mutations in rifampin-resistant Mycobacterium tuberculosis isolates in shanghai by using the amplification refractory mutation system.
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Direct detection of rifampin-resistant mycobacterium tuberculosis in respiratory specimens by PCR-DNA sequencing.
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Genetic and phenotypic characterization of drug-resistant Mycobacterium tuberculosis isolates in Hong Kong.
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Detected in multiple isolates
Positive epistasis drives the acquisition of multidrug resistance.
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Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China.
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Study of Genetic Evolution in Mycobacterium tuberculosis Isolates from Patients with Active Pulmonary Tuberculosis in the Iran and Belarus.
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mutations in rpoB gene confer resistance to rifampicin
Mutation analysis of mycobacterial rpoB genes and rifampin resistance using recombinant Mycobacterium smegmatis.
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All mutations were experimentally validated in this study.
Assessment of a 96-Well Plate Assay of Quantitative Drug Susceptibility Testing for Mycobacterium Tuberculosis Complex in China.
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Direct Detection of Rifampin and Isoniazid Resistance in Sputum Samples from Tuberculosis Patients by High-Resolution Melt Curve Analysis.
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Characterization of mutations in the rpoB gene associated with rifampin resistance in Rhodococcus equi isolated from foals.
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Mutations in the rpoB gene are associated with rifampin resistance in Rhodococcus equi.
Frequency and Type of Disputed rpoB Mutations in Mycobacterium tuberculosis Isolates from South Korea.
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Disputed rpoB mutations causing low-level resistance to rifampin
The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing.
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Mutations in rpoB were analyzed for their effect on rifampin resistance.
Disputed rpoB Mutations in Mycobacterium tuberculosis and Tuberculosis Treatment Outcomes.
Research Article
Mutations in the rpoB gene were associated with rifampin resistance in Mycobacterium tuberculosis.
Discordance in genotypic and phenotypic drug susceptibility results: time to reconsider critical concentration of rifampicin.
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Commonest mutation
A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.
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All mutations were confirmed by DNA sequencing.
Defining multidrug-resistant tuberculosis: correlating GenoType MTBDRplus assay results with minimum inhibitory concentrations.
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mutations in the rpoB gene are associated with rifampicin resistance
Molecular profiling of drug resistant isolates of Mycobacterium tuberculosis in the state of Santa Catarina, southern Brazil.
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Mutations in rpoB are associated with rifampicin resistance.
Prevalence, risk and genetic characteristics of drug-resistant tuberculosis in a tertiary care tuberculosis hospital in China.
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The complete genome sequence of unculturable Mycoplasma faucium obtained through clinical metagenomic next-generation sequencing.
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Consistent with observations in other Mycoplasma species.
Pyrosequencing for rapid detection of tuberculosis resistance in clinical isolates and sputum samples from re-treatment pulmonary tuberculosis patients.
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Profiling of rpoB mutations and MICs for rifampin and rifabutin in Mycobacterium tuberculosis.
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mutations in rpoB are associated with resistance to rifampin and rifabutin
Mixed Mycobacterium tuberculosis-Strain Infections Are Associated With Poor Treatment Outcomes Among Patients With Newly Diagnosed Tuberculosis, Independent of Pretreatment Heteroresistance.
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Mutations in the rpoB gene were associated with rifampicin resistance.
Speeding up the diagnosis of multidrug-resistant tuberculosis in a high-burden region with the use of a commercial line probe assay.
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A rapid, accurate, and low-cost method for detecting Mycobacterium tuberculosis and its drug-resistant genes in pulmonary tuberculosis: Applications of MassARRAY DNA mass spectrometry.
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Poor correlation with phenotype
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