Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Antimicrobial resistance and bacterial identification utilizing a microelectronic chip array.
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Incidence and mechanism of ciprofloxacin resistance in Campylobacter spp. isolated from commercial poultry flocks in the United Kingdom before, during, and after fluoroquinolone treatment.
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The Thr-86→Ile mutation in gyrA was the most common mutation associated with ciprofloxacin and nalidixic acid resistance.
Molecular evidence for the thriving of Campylobacter jejuni ST-4526 in Japan.
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Single base mutation in gyrA at Thr86 plays a role in increasing the resistance of nalidixic acid (NA) and fluoroquinolones in Campylobacter.
WGS-Based Prediction and Analysis of Antimicrobial Resistance in Campylobacter jejuni Isolates From Israel.
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Prediction of antimicrobial resistance in clinical Campylobacter jejuni isolates from whole-genome sequencing data.
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Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile.
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This mutation confers high levels of resistance to fluoroquinolones.
Distribution of CRISPR Types in Fluoroquinolone-Resistant Campylobacter jejuni Isolates.
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Mutations in the QRDR of gyrA are associated with fluoroquinolone resistance in C. jejuni.
Occurrence, Antimicrobial Resistance, and Molecular Characterization of Campylobacter spp. in Intensive Pig Production in South Africa.
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High-throughput sequencing reveals genetic determinants associated with antibiotic resistance in Campylobacter spp. from farm-to-fork.
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Mutations in the QRDR of gyrA confer resistance to quinolones.
Core Genome MLST for Source Attribution of Campylobacter coli.
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Molecular Detection of Fluoroquinolone Resistance among Multidrug-, Extensively Drug-, and Pan-Drug-Resistant Campylobacter Species in Egypt.
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Chromosomal mutation in the QRDR of the gyrA gene
Systematic Evaluation of Whole-Genome Sequencing Based Prediction of Antimicrobial Resistance in Campylobacter jejuni and C. coli.
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Confers resistance to quinolones
Genomic Relatedness, Antibiotic Resistance and Virulence Traits of Campylobacter jejuni HS19 Isolates From Cattle in China Indicate Pathogenic Potential.
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Genomic diversity and antimicrobial resistance of Campylobacter spp. from humans and livestock in Nigeria.
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Risk factors for fluoroquinolone- and macrolide-resistance among swine Campylobacter coli using multi-layered chain graphs.
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Prevalence and genetic characteristics of Campylobacter jejuni from laying-hens in Hubei Province, China.
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Genomic epidemiology and the evolution of erm(B)-mediated macrolide resistance in Campylobacter.
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Confers resistance to quinolones
Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure.
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The C257T mutation in gyrA confers high-level fluoroquinolone resistance and enhances in vivo fitness of Campylobacter jejuni.
Genomic Analysis Reveals the Genetic Determinants Associated With Antibiotic Resistance in the Zoonotic Pathogen Campylobacter spp. Distributed Globally.
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Mutations in gyrA are associated with fluoroquinolone resistance.
Genotyping and Antibiotic Resistance Traits in Campylobacter jejuni and coli From Pigs and Wild Boars in Italy.
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Antibiotic Resistance Profiles and Molecular Mechanisms of Campylobacter From Chicken and Pig in China.
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Phenotypic and Molecular Patterns of Resistance among Campylobacter coli and Campylobacter jejuni Isolates, from Pig Farms.
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Ongoing Outbreak of Extensively Drug-Resistant Campylobacter jejuni Infections Associated With US Pet Store Puppies, 2016-2020.
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Differences in Genotype and Antimicrobial Resistance between Campylobacter spp. Isolated from Organic and Conventionally Produced Chickens in Sweden.
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WQ-3810, a fluoroquinolone with difluoropyridine derivative as the R1 group exerts high potency against quinolone-resistant Campylobacter jejuni.
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Campylobacter coli of porcine origin exhibits an open pan-genome within a single clonal complex: insights from comparative genomic analysis.
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Antimicrobial resistance and genomic characteristics of Campylobacter spp. From Australian meat chickens with A follow up investigation.
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T86I mutation in the QRDR of gyrA reduces sensitivity to quinolones
Phenotypic and whole genome-based characterization of antibiotic resistance of Campylobacter jejuni isolates from chicken livers.
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Point mutation in the subunit A of the DNA gyrase gene
Genomic analysis and antimicrobial resistance in human- and poultry-derived Campylobacter jejuni isolates from Hangzhou, China.
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The T86I mutation was predominant, detected in 91.5% (43/47) of isolates.
Antimicrobial susceptibilities of thermophilic Campylobacter from humans, swine, and chicken broilers.
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mutation in gyrA leads to quinolone resistance
Development of experimental genetic tools for Campylobacter fetus.
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Mutation in gyrA leads to ciprofloxacin resistance
Clonal population structure and antimicrobial resistance of Campylobacter jejuni in chicken meat from Belgium.
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Mutation in gyrA confers resistance to fluoroquinolones.
Whole Genome Sequence-Based Prediction of Resistance Determinants in High-Level Multidrug-Resistant Campylobacter jejuni Isolates in Lithuania.
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Whole genome-based characterisation of antimicrobial resistance and genetic diversity in Campylobacter jejuni and Campylobacter coli from ruminants.
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mutation in gyrA gene associated with quinolone resistance
Natural Horizontal Gene Transfer of Antimicrobial Resistance Genes in Campylobacter spp. From Turkeys and Swine.
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Antimicrobial Resistance in Campylobacter coli and Campylobacter jejuni from Human Campylobacteriosis in Taiwan, 2016 to 2019.
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Mutations in gyrA confer resistance to quinolones and fluoroquinolones.
Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018.
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Genomic epidemiology and genetic characteristics of clinical Campylobacter species cocirculating in West Bengal, India, 2019, using whole genome analysis.
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Strain sharing and mobile genetic elements shape the interconnected resistomes of Campylobacter coli in Brazil.
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Characterization and Phylogenetic Analysis of Campylobacter Species Isolated from Paediatric Stool and Water Samples in the Northwest Province, South Africa.
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Genomic Analysis of Emerging Florfenicol-Resistant Campylobacter coli Isolated from the Cecal Contents of Cattle in the United States.
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mutation in the QRDR of gyrA
Whole-genome comparative analysis of Campylobacter jejuni strains isolated from patients with diarrhea in northeastern Poland.
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Present in all isolates
Molecular characterization of Campylobacter causing human clinical infection using whole-genome sequencing: Virulence, antimicrobial resistance and phylogeny in Ireland.
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Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry.
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Only mutations in the quinolone resistance-determining region (QRDR) of gyrA were regarded to be the determinants of resistance.
Hyper-Aerotolerant Campylobacter coli from Duck Sources and Its Potential Threat to Public Health: Virulence, Antimicrobial Resistance, and Genetic Relatedness.
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Mutation in the quinolone resistance-determining region (QRDR) of gyrA conferring resistance to quinolones.
Comparison of different technologies for the decipherment of the whole genome sequence of Campylobacter jejuni BfR-CA-14430.
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Point mutation in the gyrase subunit A conferring resistance against (fluoro-)quinolones.
Antimicrobial resistance patterns and molecular resistance markers of Campylobacter jejuni isolates from human diarrheal cases.
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Increasing prevalence of a fluoroquinolone resistance mutation amongst Campylobacter jejuni isolates from four human infectious intestinal disease studies in the United Kingdom.
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The T86I mutation in gyrA is associated with fluoroquinolone resistance.
Prevalence, Population Diversity and Antimicrobial Resistance of Campylobacter coli Isolated in Italian Swine at Slaughterhouse.
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Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp.
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Overview of Ecology and Aspects of Antibiotic Resistance in Campylobacter spp. Isolated from Free-Grazing Chicken Tissues in Rural Households.
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Integrative and Conjugative Elements and Prophage DNA as Carriers of Resistance Genes in Erysipelothrix rhusiopathiae Strains from Domestic Geese in Poland.
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Characterization of antimicrobial resistance patterns and detection of virulence genes in Campylobacter isolates in Italy.
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The mutation T86-I was found in 83 strains resistant to ciprofloxacin and/or nalidixic acid.
Investigating the host specificity of Campylobacter jejuni and Campylobacter coli by sequencing gyrase subunit A.
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The Thr86Ile substitution in gyrA is associated with quinolone resistance.
Trends in fluoroquinolone resistance in Campylobacter.
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Single point mutation in the gyrA gene within the QRDR is the most frequent mechanism of CIP resistance.
Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin.
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Fluoroquinolone-Resistant Salmonella enterica, Campylobacter spp., and Arcobacter butzleri from Local and Imported Poultry Meat in Kumasi, Ghana.
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Comparison of Antimicrobial Susceptibility Profiles of Thermotolerant Campylobacter spp. Isolated from Human and Poultry Samples in Georgia (Caucasus).
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The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic.
Review
Whole-genome-based characterization of Campylobacter jejuni from human patients with gastroenteritis collected over an 18 year period reveals increasing prevalence of antimicrobial resistance.
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T86I is the most prevalent mutation in quinolone-resistant isolates
Genomic insight into Campylobacter jejuni isolated from commercial turkey flocks in Germany using whole-genome sequencing analysis.
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associated with fluoroquinolone resistance
Antimicrobial resistance profiles of Campylobacter jejuni and Salmonella spp. isolated from enteritis patients in Japan.
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Detected in 31 STs
Prevalence, genomic characterization and antimicrobial resistance of Campylobacter spp. isolates in pets in Shenzhen, China.
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Genomic and Antimicrobial Surveillance of Campylobacter Population in Italian Poultry.
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First Report of Campylobacter jejuni Strains Belonging to ST-21 Clonal Complex Isolated from Human, Poultry and Wild Birds in Croatia: Antimicrobial Resistance and Genetic Distance.
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Whole-Genome Sequencing-Based Profiling of Antimicrobial Resistance Genes and Core-Genome Multilocus Sequence Typing of Campylobacter jejuni from Different Sources in Lithuania.
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Vertebral osteomyelitis caused by Campylobacter jejuni in an immunocompetent patient.
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Confers resistance to ciprofloxacin.
Campylobacter jejuni in hospitalized patients with diarrhea, Kolkata, India.
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Antimicrobial resistance mechanisms among Campylobacter.
Review
The Thr86Ile mutation in gyrA is the most frequent mutation associated with fluoroquinolone resistance in Campylobacter.
Virulence and Antimicrobial Resistance in Campylobacter spp. from a Peruvian Pediatric Cohort.
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Subtype-Specific Selection for Resistance to Fluoroquinolones but Not to Tetracyclines Is Evident in Campylobacter jejuni Isolates from Beef Cattle in Confined Feeding Operations in Southern Alberta, Canada.
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Mutations in the quinolone resistance-determining region (QRDR) of the gyrA gene confer resistance to ciprofloxacin and nalidixic acid.
Prevalence of Genetic Determinants and Phenotypic Resistance to Ciprofloxacin in Campylobacter jejuni from Lithuania.
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Acquisition of fluoroquinolone resistance leads to increased biofilm formation and pathogenicity in Campylobacter jejuni.
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Additional mutations in gyrA (Asp90Asn) and gyrB (Leu458Lys) were observed in some ciprofloxacin-resistant strains.
Molecular Characterization and Antimicrobial Susceptibility of C. jejuni Isolates from Italian Wild Bird Populations.
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Microevolution of Campylobacter jejuni during long-term infection in an immunocompromised host.
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Mutations in gyrA contribute to fluoroquinolone resistance.
The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2016.
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Point mutation in gyrA gene responsible for fluoroquinolone resistance.
Validation of the T86I mutation in the gyrA gene as a highly reliable real time PCR target to detect Fluoroquinolone-resistant Campylobacter jejuni.
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Molecular characterization of Campylobacter spp. recovered from beef, chicken, lamb and pork products at retail in Australia.
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Present in isolates from all sources except beef.
Campylobacter jejuni from Canine and Bovine Cases of Campylobacteriosis Express High Antimicrobial Resistance Rates against (Fluoro)quinolones and Tetracyclines.
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associated with (fluoro)quinolone resistance
Investigation of Antimicrobial Susceptibilities and Resistance Genes of Campylobacter Isolates from Patients in Edirne, Turkey.
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Mutation detected in all ciprofloxacin-resistant isolates
Virulence Profiling, Multidrug Resistance and Molecular Mechanisms of Campylobacter Strains from Chicken Carcasses in Tunisia.
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Five centuries of genome evolution and multi-host adaptation of Campylobacter jejuni in Brazil.
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Transmission of dominant strains of Campylobacter jejuni and Campylobacter coli between farms and retail stores in Ecuador: Genetic diversity and antimicrobial resistance.
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Genetic Diversity, Virulence, and Antibiotic Resistance Determinants of Campylobacter jejuni Isolates in Romania.
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Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance mechanisms and trends in human isolates.
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Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations.
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gyrA
Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter spp.
Review
Identification of the main quinolone resistance determinant in Campylobacter jejuni and Campylobacter coli by MAMA-DEG PCR.
Research Article
Campylobacter jejuni gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003789
Serotypes, Antibiotic Susceptibility, Genotypic Virulence Profiles and SpaA Variants of Erysipelothrix rhusiopathiae Strains Isolated from Pigs in Poland.
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Erysipelothrix rhusiopathiae gyrA with mutation conferring resistance to enrofloxacin; CARD accession: CARD:3007544
gyrA polymorphism in Campylobacter jejuni: detection of gyrA mutations in 162 C. jejuni isolates by single-strand conformation polymorphism and DNA sequencing.
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gyrA
Fluoroquinolone resistance in Campylobacter species from man and animals: detection of mutations in topoisomerase genes.
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gyrA
Analysis of gyrA mutations in quinolone-resistant and -susceptible Campylobacter jejuni isolates from retail poultry and human clinical isolates by non-radioactive single-strand conformation polymorphism analysis and DNA sequencing.
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gyrA
Two distinct mutations in gyrA lead to ciprofloxacin and nalidixic acid resistance in Campylobacter coli and Campylobacter jejuni isolated from chickens and beef cattle.
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gyrA
Quantitative assessment and genomic profiling of Campylobacter dynamics in poultry processing: a case study in the United Arab Emirates integrated abattoir system.
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gyrA
Multiplex strategy for multilocus sequence typing, fla typing, and genetic determination of antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolates collected in Switzerland.
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mutation in gyrA confers quinolone resistance
Genomic Analysis and Antimicrobial Resistance of Campylobacter jejuni and Campylobacter coli in Peru.
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Both mutations were found in C. jejuni and C. coli.
Emergence of a Potent Multidrug Efflux Pump Variant That Enhances Campylobacter Resistance to Multiple Antibiotics.
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The C257T mutation in gyrA enhances fluoroquinolone resistance when combined with RE-cmeABC.
Genomic Characterization of Fluoroquinolone-Resistant Thermophilic Campylobacter Strains Isolated from Layer Chicken Feces in Gangneung, South Korea by Whole-Genome Sequencing.
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Population Genetics and Antimicrobial Susceptibility of Canine Campylobacter Isolates Collected before and after a Raw Feeding Experiment.
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Point mutation C257T in gyrA leads to Thr-86-Met substitution, causing reduced susceptibility to ciprofloxacin and nalidixic acid.
Antimicrobial Susceptibility Profiles of Human Campylobacter jejuni Isolates and Association with Phylogenetic Lineages.
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Point mutations in gyrA confer resistance to fluoroquinolones.
Genotypes and antibiotic resistances of Campylobacter jejuni isolates from cattle and pigeons in dairy farms.
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The C257T mutation in the gyrA gene leads to quinolone resistance.
Phenotypic and Genotypic Examination of Antimicrobial Resistance in Thermophilic Campylobacter Species Isolated from Poultry in Turkey.
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Mutation in DNA gyrase subunit A responsible for quinolone resistance
Genomic Insights into the Increased Occurrence of Campylobacteriosis Caused by Antimicrobial-Resistant Campylobacter coli.
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Genetic characteristics, antimicrobial susceptibility, and virulence genes distribution of Campylobacter isolated from local dual-purpose chickens in central China.
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Should We Consider Them as a Threat? Antimicrobial Resistance, Virulence Potential and Genetic Diversity of Campylobacter spp. Isolated from Varsovian Dogs.
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Prevalence and antimicrobial resistance of Campylobacter species in shelter-housed healthy and diarrheic cats and dogs in Turkey.
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The Thr-86-Ile mutation was the most common change detected in the gyrA gene in the quinolone-resistant isolates.
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