Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations.
Research Article
Mutations in penA are critical for intermediate resistance to expanded-spectrum cephalosporins in Neisseria gonorrhoeae.
penA
Resistance to β-Lactams in Neisseria ssp Due to Chromosomally Encoded Penicillin-Binding Proteins.
Review
Mutations in penA contribute to β-lactam resistance in Neisseria spp.
The antimicrobial resistance landscape of Neisseria gonorrhoeae in New Zealand from November 2018 to March 2019 and the role of sexual orientation in transmission.
Research Article
Mutations in penA contribute to reduced susceptibility to ceftriaxone and cefixime.
Antibiotic-resistance mutations in penicillin-binding protein 2 from the ceftriaxone-resistant Neisseria gonorrhoeae strain H041 strike a delicate balance between increasing resistance and maintaining transpeptidase activity.
Research Article
Mutations in penA confer resistance to ceftriaxone and cefixime
Amino acid substitutions in mosaic penicillin-binding protein 2 associated with reduced susceptibility to cefixime in clinical isolates of Neisseria gonorrhoeae.
Research Article
The G545S mutation in penA was identified as a key mutation contributing to reduced susceptibility to cefixime and other cephems.
WGS to predict antibiotic MICs for Neisseria gonorrhoeae.
Research Article
Reliability of Genetic Alterations in Predicting Ceftriaxone Resistance in Neisseria gonorrhoeae Globally.
Research Article
The use of cephalosporins for gonorrhea: the impending problem of resistance.
Review
Multiple mutations in penA contribute to cephalosporin resistance.
Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3-β4 loop to favor a low-affinity drug-binding state.
Research Article
All mutations are in the β3–β4 loop of PBP2 and contribute to ceftriaxone resistance by altering the conformational dynamics of the protein.
Hydrogel Droplet Microarray for Genotyping Antimicrobial Resistance Determinants in Neisseria gonorrhoeae Isolates.
Research Article
Molecular Detection of Mutations in the penA and 23S rRNA Genes of Neisseria gonorrhoeae Related to Decreased Cephalosporin and Azithromycin Susceptibility in Rectal Specimens from Men Who Have Sex with Men (MSM) in Lima, Peru.
Research Article
mutations in penA gene associated with decreased susceptibility to cephalosporins
Utility of specimens positive for Neisseria gonorrhoeae by the Aptima Combo 2 assay for assessment of strain diversity and antibiotic resistance.
Research Article
Azithromycin-resistant Neisseria gonorrhoeae isolates in Guangzhou, China (2009-2013): coevolution with decreased susceptibilities to ceftriaxone and genetic characteristics.
Research Article
Mutations in penA were associated with decreased susceptibility to ceftriaxone.
Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.
Research Article
Evolution of Ceftriaxone Resistance of Penicillin-Binding Proteins 2 Revealed by Molecular Modeling.
Research Article
Mutations in penA gene contribute to ceftriaxone resistance in Neisseria gonorrhoeae.
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future.
Review
Associated with decreased susceptibility to cefixime and ceftriaxone.
Mutation indicates mosaic penA gene
Establishing Novel Molecular Algorithms to Predict Decreased Susceptibility to Ceftriaxone in Neisseria gonorrhoeae Strains.
Review
mutations in penA are associated with decreased susceptibility to ceftriaxone
Association of Phylogenomic Relatedness among Neisseria gonorrhoeae Strains with Antimicrobial Resistance, Austria, 2016-2020.
Research Article
Mutations in penA were associated with cefinase positivity and cefixime resistance
Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants of Neisseria gonorrhoeae.
Review
mutations in penA are critical for resistance to ceftriaxone and cefixime
Antibiotic Resistance in Neisseria gonorrhoeae: Challenges in Research and Treatment.
Research Article
Mutations in penA are associated with ceftriaxone resistance.
Mercury--an element of mystery.
Research Article
penA
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