Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis.
Research Article
The Structural Basis of Mycobacterium tuberculosis RpoB Drug-Resistant Clinical Mutations on Rifampicin Drug Binding.
Research Article
All mutations were identified in the RIF resistance-determining region (RRDR) of rpoB.
Molecular characterization of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates identifies local transmission of infection in Kuwait, a country with a low incidence of TB and MDR-TB.
Research Article
First insights into the phylogenetic diversity of Mycobacterium tuberculosis in Kuwait and evaluation of REBA MTB-MDR assay for rapid detection of MDR-TB.
Research Article
Investigation of Multi-Subunit Mycobacterium tuberculosis DNA-Directed RNA Polymerase and Its Rifampicin Resistant Mutants.
Research Article
All mutations are located in the RIF-resistance-determining region (RRDR) of rpoB.
Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae.
Research Article
Mutations in the rpoB gene were identified in relapsed leprosy cases and analyzed for their structural and functional effects on rifampin resistance.
Probing the Molecular Mechanism of Rifampin Resistance Caused by the Point Mutations S456L and D441V on Mycobacterium tuberculosis RNA Polymerase through Gaussian Accelerated Molecular Dynamics Simulation.
Research Article
The D441V mutation in rpoB was shown to confer rifampin resistance.
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