ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeS84K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Quinolone
Organisms: Staphylococcus aureus, Streptococcus pneumoniae
Papers: 1

Paper Information1

In vitro activities of novel nonfluorinated quinolones PGE 9262932 and PGE 9509924 against clinical isolates of Staphylococcus aureus and Streptococcus pneumoniae with defined mutations in DNA gyrase and topoisomerase IV.

PMID 12019071 · 2002

Mutations in gyrA are associated with quinolone resistance.

Mutation Information

gyrA: p.S84K

Protein Change: S84K
Organisms: Staphylococcus aureus, Streptococcus pneumoniae
Confers Resistance To: Quinolone
Source Database: Reslit

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