ResLit - Antimicrobial Resistance Gene & Mutation Database

GenerdxA

oxygen-insensitive NADPH nitroreductase

Protein ChangeQ50*

Nucleotide ChangeC149T

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReslit

Overview

Mechanism: nonsense mutation
Resistance To: metronidazole
Organisms: Helicobacter pylori
Papers: 2

Paper Information2

Molecular characterization and prevalence of antibiotic resistance in Helicobacter pylori isolates in Kuala Lumpur, Malaysia.

Research Article

PMID 31632095 · 2019

Mutation Information

rdxA: p.Q50* / c.C149T

Protein Change: Q50*
Nucleotide Change: C149T
Organisms: Helicobacter pylori
Confers Resistance To: metronidazole
Validation Method: sequencing
Source Database: Reslit

High Prevalence of Antibiotic Resistance in Iranian Helicobacter pylori Isolates: Importance of Functional and Mutational Analysis of Resistance Genes and Virulence Genotyping.

Research Article

PMID 31744181 · 2019

Helicobacter pylori rdxA mutation conferring resistance to metronidazole; CARD accession: CARD:3007055

Mutation Information

rdxA: p.Q50*

Protein Change: Q50*
Organisms: Helicobacter pylori
Confers Resistance To: metronidazole
Effect on Function: nonsense mutation
Validation Method: sequencing
Source Database: ReslitCard Database

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