ResLit - Antimicrobial Resistance Gene & Mutation Database

GenefolP1

Protein ChangeR54G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: dapsone
Organisms: Mycobacterium smegmatis, Mycobacterium leprae
Papers: 2

Paper Information2

Mutation analysis of the Mycobacterium leprae folP1 gene and dapsone resistance.

Research Article

PMID 21115799 · 2011

Mutation Information

folP1: p.R54G

Protein Change: R54G
Organisms: Mycobacterium smegmatis
Confers Resistance To: dapsone
Validation Method: dapsone MIC testing
Source Database: Reslit

Nested PCR and the TaqMan SNP Genotyping Assay enhanced the sensitivity of drug resistance testing of Mycobacterium leprae using clinical specimens of leprosy patients.

Research Article

PMID 31881061 · 2019

Mutation Information

folP1: p.R54G

Protein Change: R54G
Organisms: Mycobacterium leprae
Confers Resistance To: dapsone
Validation Method: Sanger sequencing and TaqMan SNP genotyping
Source Database: Reslit

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