ResLit - Antimicrobial Resistance Gene & Mutation Database

Nucleotide ChangeG285A

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Overview

Mechanism: decreased affinity for ciprofloxacin
Resistance To: fluoroquinolones, ciprofloxacin
Organisms: Mycoplasma genitalium, Escherichia coli, Pseudomonas aeruginosa, Campylobacter, Neisseria gonorrhoeae +1 more
Papers: 2

Paper Information2

Mycoplasma genitalium Antimicrobial Resistance in Community and Sexual Health Clinic Patients, Auckland, New Zealand.

Research Article

Mutations in gyrA at codon 95 were detected in 6 patients, 5 of whom were SHC attendees.

The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic.

Review

Protein Change: D95N
Nucleotide Change: G285A
Organisms: Escherichia coli, Pseudomonas aeruginosa, Campylobacter, Neisseria gonorrhoeae, Neisseria meningitidis
Confers Resistance To: ciprofloxacin
Effect on Function: decreased affinity for ciprofloxacin
Validation Method: sequencing and mutation analysis
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

Browse AMR Mutations