Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
The whole-genome sequencing in predicting Mycobacterium tuberculosis drug susceptibility and resistance in Papua, Indonesia.
Research Article
Drug-Resistant Characteristics, Genetic Diversity, and Transmission Dynamics of Rifampicin-Resistant Mycobacterium tuberculosis in Hunan, China, Revealed by Whole-Genome Sequencing.
Research Article
Molecular Epidemiology of Mycobacterium tuberculosis Complex Strains in Urban and Slum Settings of Nairobi, Kenya.
Research Article
Multi-drug resistance and compensatory mutations in Mycobacterium tuberculosis in Vietnam.
Research Article
Diverse impacts of different rpoB mutations on the anti-tuberculosis efficacy of capreomycin.
Research Article
Mutations at codon 435 (D435G, D435V) conferred increased CAP tolerance, while mutations at codon 445 (H445Y, H445R) enhanced CAP bactericidal effect.
Beyond Hotspot Mutations: Diagnostic Relevance of High Frequency, Low Frequency, and Disputed rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis.
Review
Mutations in rpoB are responsible for rifampicin resistance in Mycobacterium tuberculosis.
rpoB gene mutations in rifampin-resistant Mycobacterium tuberculosis isolates from rural areas of Zhejiang, China.
Research Article
Predicting rifampicin resistance mutations in bacterial RNA polymerase subunit beta based on majority consensus.
Research Article
Mutations in the rifampicin resistance-determining regions (RRDRs) of RpoB were analyzed.
Molecular characterization of rpoB gene mutations in isolates from tuberculosis patients in Cubal, Republic of Angola.
Research Article
mutations in rpoB associated with rifampicin resistance
rpoB Mutations and Effects on Rifampin Resistance in Mycobacterium tuberculosis.
Research Article
These mutations were identified as contributing to rifampin resistance through experimental validation.
A modified decision tree approach to improve the prediction and mutation discovery for drug resistance in Mycobacterium tuberculosis.
Research Article
Transmission of multidrug-resistant Mycobacterium tuberculosis in Wuhan, China: A retrospective molecular epidemiological study.
Research Article
Whole genome sequencing analysis of Mycobacterium tuberculosis reveals circulating strain types and drug-resistance mutations in the Philippines.
Research Article
Common mutations underlying MDR-TB for rifampicin.
Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates.
Research Article
Mutations in rpoB are associated with rifampicin resistance.
Whole-genome sequencing reveals transmission pattern and drug resistance of Mycobacterium tuberculosis intra- or inter-hosts.
Research Article
Impact of rpoB gene mutations and Rifampicin-resistance levels on treatment outcomes in Rifampicin-resistant tuberculosis.
Research Article
Mutations in the rpoB gene were associated with rifampicin resistance and treatment outcomes.
Efflux pumps positively contribute to rifampin resistance in rpoB mutant Mycobacterium tuberculosis.
Research Article
Mutations in rpoB gene were associated with increased rifampin resistance.
Prospective Comparative Evaluation of the Xpert MTB/RIF and Xpert MTB/RIF Ultra Assays for Detecting Mycobacterium tuberculosis and Rifampin Resistance in High-resource, Intermediate-burden Settings.
Research Article
Novel Chemical Scaffolds for Inhibition of Rifamycin-Resistant RNA Polymerase Discovered from High-Throughput Screening.
Research Article
Mutations in the rpoB gene were analyzed for their impact on rifampin resistance.
Genotypic distribution of multidrug-resistant and extensively drug-resistant tuberculosis in northern Thailand.
Research Article
Comparative Analytical Evaluation of Four Centralized Platforms for the Detection of Mycobacterium tuberculosis Complex and Resistance to Rifampicin and Isoniazid.
Research Article
Understanding Rifampicin Resistance in Tuberculosis through a Computational Approach.
Research Article
Integration of published information into a resistance-associated mutation database for Mycobacterium tuberculosis.
Review
Evaluation of GenoType MTBDRplus for the rapid detection of drug-resistant tuberculosis in Ghana.
Research Article
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance.
Research Article
Characterization of Mutations Conferring Resistance to Rifampin in Mycobacterium tuberculosis Clinical Strains.
Research Article
Mutations in the rpoB gene were analyzed for their role in rifampin resistance.
Mycobacterium tuberculosis whole genome sequencing provides insights into the Manila strain and drug-resistance mutations in the Philippines.
Research Article
Confirmed in the study
Compensatory mutations are associated with increased in vitro growth in resistant clinical samples of Mycobacterium tuberculosis.
Research Article
mutations associated with rifampicin resistance
Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.
Research Article
The rpoB-H445Y mutation was identified in rifampicin-resistant Mtb HN878 clones.
rpoB Mutations are Associated with Variable Levels of Rifampin and Rifabutin Resistance in Mycobacterium tuberculosis.
Research Article
Host-pathogen relationship in retreated tuberculosis with major rifampicin resistance-conferring mutations.
Research Article
Both mutations are linked to rifampicin resistance and differ in prevalence across Mtb lineages.
Molecular characterization of genetic mutations with fitness loss in pulmonary tuberculosis patients associated with HIV co-infection in Northwest Amhara, Ethiopia.
Research Article
Detected in MDR-TB isolates
Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique.
Research Article
Insights into the in-vitro Susceptibility and Drug-Drug Interaction Profiles Against Drug-Resistant and Susceptible Mycobacterium tuberculosis Clinical Isolates in Amhara, Ethiopia.
Research Article
Evaluation of Whole-Genome Sequencing for Mycobacterial Species Identification and Drug Susceptibility Testing in a Clinical Setting: a Large-Scale Prospective Assessment of Performance against Line Probe Assays and Phenotyping.
Research Article
Direct Whole-Genome Sequencing of Sputum Accurately Identifies Drug-Resistant Mycobacterium tuberculosis Faster than MGIT Culture Sequencing.
Research Article
Mycobacterium tuberculosis Complex Lineage 3 as Causative Agent of Pulmonary Tuberculosis, Eastern Sudan
Research Article
Detection of drug resistant Mycobacterium tuberculosis by high-throughput sequencing of DNA isolated from acid fast bacilli smears.
Research Article
Mutations in rpoB are associated with rifampicin resistance.
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics.
Research Article
mutations in rpoB are associated with rifampicin resistance
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China.
Research Article
All mutations were experimentally validated in this study.
Evaluation of Whole Genome Sequencing-Based Predictions of Antimicrobial Resistance to TB First Line Agents: A Lesson from 5 Years of Data.
Research Article
MUBII-TB-DB: a database of mutations associated with antibiotic resistance in Mycobacterium tuberculosis.
Research Article
Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.
Research Article
Detection of first- and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing.
Research Article
Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology.
Research Article
Tuberculosis drug resistance mutation database.
Research Article
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.
Research Article
Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis.
Review
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.
Research Article
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates.
Research Article
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
Distribution of rpoB mutations among multidrug-resistant Mycobacterium tuberculosis (MDRTB) strains from Thailand and development of a rapid method for mutation detection.
Research Article
Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283
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