Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Detection of Helicobacter pylori resistance to clarithromycin and fluoroquinolones in Brazil: A national survey.
Distribution of gyrA mutations in fluoroquinolone-resistant Helicobacter pylori strains.
Mutations in the gyrA gene were associated with fluoroquinolone resistance
Phenotypic and Genotypic Antibiotic Resistance Patterns in Helicobacter pylori Strains From Ethnically Diverse Population in México.
A Survey of Helicobacter pylori Antibiotic-Resistant Genotypes and Strain Lineages by Whole-Genome Sequencing in China.
Development and Validation of Multiplex Quantitative PCR Assay for Detection of Helicobacter pylori and Mutations Conferring Resistance to Clarithromycin and Levofloxacin in Gastric Biopsy.
Rapid Detection of Quinolone Resistance Mutations in gyrA of Helicobacter pylori by Real-Time PCR.
Mutations in the quinolone-resistance-determining region (QRDR) of the gyrA gene confer resistance to quinolones.
Susceptibility-guided bismuth quadruple therapies for resistant Helicobacter pylori infections.
Whole-genome sequencing analyses and antibiotic resistance situation of 48 Helicobacter pylori strains isolated in Zhejiang, China.
point mutation
Analysis of antimicrobial resistance patterns and genetic mutations in Helicobacter pylori from West Bengal, India depicting escalating clarithromycin and high levofloxacin resistance.
novel mutation
Genomic insights into antibiotic resistance, virulence traits and phylogenetic lineages of 141 clinical Helicobacter pylori isolates from Eastern China.
Rapid detection of point mutations conferring resistance to fluoroquinolone in gyrA of Helicobacter pylori by allele-specific PCR.
Recent Insights into Antibiotic Resistance in Helicobacter pylori Eradication.
Mutations in gyrA are associated with fluoroquinolone resistance.
Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples.
Molecular and Proteomic Analysis of Levofloxacin and Metronidazole Resistant Helicobacter pylori.
Prevalence of Helicobacter pylori Antimicrobial Resistance Among Chilean Patients.
Mutations in the quinolone-resistance determining region (QRDR) of the gyrA gene are the main cause of quinolone resistance in H. pylori.
Analysis of antibiotic susceptibility and genomic characteristics of Helicobacter pylori by whole-genome resequencing in Northern China.
Comparison of Culture With Antibiogram to Next-Generation Sequencing Using Bacterial Isolates and Formalin-Fixed, Paraffin-Embedded Gastric Biopsies.
Biomarker Characterization and Prediction of Virulence and Antibiotic Resistance from Helicobacter pylori Next Generation Sequencing Data.
Helicobacter pylori Infection in Colombia: Phylogeny, Resistome, and Virulome.
Analysis of the status and risk factors for Helicobacter pylori infection and drug resistance in the Lianyungang area, China.
Development and validation of next-generation sequencing panel for personalized Helicobacter pylori eradication treatment targeting multiple species.
missense mutation in gyra associated with levofloxacin resistance
Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pylori.
Multiple mutations in the QRDR of gyrA contribute to fluoroquinolone resistance in H. pylori.
Helicobacter pylori eradication by sitafloxacin-lansoprazole combination and sitafloxacin pharmacokinetics in Mongolian gerbils and its in vitro activity and resistance development.
Mutations in gyrA were associated with increased MICs for levofloxacin and sitafloxacin.
Surveillance of Levofloxacin Resistance in Helicobacter pylori Isolates in Bogotá-Colombia (2009-2014).
Mutations in gyrA are associated with levofloxacin resistance in H. pylori.
Clarithromycin-Based Triple Therapy is Still Useful as an Initial Treatment for Helicobacter pylori Infection in the Dominican Republic.
Noninvasive molecular analysis of Helicobacter pylori: Is it time for tailored first-line therapy?
Five point mutations in this site, able to induce resistance to this antibiotic, have been observed.
Secondary Antibiotic Resistance, Correlation between Genotypic and Phenotypic Methods and Treatment in Helicobacter pylori Infected Patients: A Retrospective Study.
Genotype profiles of Helicobacter pylori from gastric biopsies and strains with antimicrobial-induced resistance.
Comparison of the Diagnostic Performance of qPCR, Sanger Sequencing, and Whole-Genome Sequencing in Determining Clarithromycin and Levofloxacin Resistance in Helicobacter pylori.
Genomic Analysis of Antimicrobial Resistance Genotype-to-Phenotype Agreement in Helicobacter pylori.
Includes novel point mutations found in resistant isolates.
Genetic Determinants of Clarithromycin and Fluoroquinolones Resistance in Helicobacter pylori in Serbia.
Helicobacter pylori resistance in Hainan Province, China: investigating phenotypes and genotypes through whole-genome sequencing.
Detection of Helicobacter pylori and the Genotypes of Resistance to Clarithromycin, Fluoroquinolones, and Metronidazole in Gastric Biopsies: An In Silico Analysis to Help Understand Antibiotic Resistance.
Current rates of Helicobacter pylori infection and antibiotic resistance in the eastern coast of China: a single center study.
Clinical evaluation of a novel H. pylori fecal molecular diagnosis kit (multiplex RT-PCR method) for detecting clarithromycin and fluoroquinolones resistance using stool samples.
Antibiotic Resistance and Genetic Determinants of Helicobacter pylori in Oman: Insights from Phenotypic and Whole-Genome Analysis.
Assessment of target-enrichment library preparation and next-generation sequencing of paraffin-embedded gastric biopsies for H. pylori diagnosis and evaluation of virulome and resistome.
Detected in samples 4, 5, 7, 10, 11, 13, 14, 17, 19, 20, 22, 23, 26, 27, 29
Resistance to Clarithromycin and Fluoroquinolones in Helicobacter pylori Isolates: A Prospective Molecular Analysis in Western Romania.
gyr 87MUT profile
Mechanisms of Helicobacter pylori antibiotic resistance and molecular testing.
A Next-Generation Sequencing-Based Approach to Identify Genetic Determinants of Antibiotic Resistance in Cambodian Helicobacter pylori Clinical Isolates.
Helicobacter pylori Mutations Conferring Resistance to Fluoroquinolones and Clarithromycin among Dyspeptic Patients Attending a Tertiary Hospital, Tanzania.
A92T detected for the first time in H. pylori
The Prevalence, Risk Factors, and Antimicrobial Resistance Determinants of Helicobacter pylori Detected in Dyspeptic Patients in North-Central Bangladesh.
Functional and molecular surveillance of Helicobacter pylori antibiotic resistance in Kuala Lumpur.
The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in Helicobacter pylori.
Microarray-Based Detection and Clinical Evaluation for Helicobacter pylori Resistance to Clarithromycin or Levofloxacin and the Genotype of CYP2C19 in 1083 Patients.
Molecular Patterns of Resistance Among Helicobacter pylori Strains in South-Western Poland.
Mutations Related to Antibiotics Resistance in Helicobacter pylori Clinical Isolates from Bangladesh.
The State of the Art of Molecular Fecal Investigations for Helicobacter pylori (H. pylori) Antibiotic Resistances.
Antibiotic resistance in Helicobacter pylori: From potential biomolecular mechanisms to clinical practice.
Whole Genome Sequencing for Studying Helicobacter pylori Antimicrobial Resistance.
The Helicobacter pylori single nucleotide polymorphisms SNPs associated with multiple therapy resistance in Colombia.
Antibiotic resistance of Helicobacter pylori in Nanjing, China: a cross-section study from 2018 to 2023.
Multiple gyrA mutations were identified, including single, double, and one triple site mutation.
Occurrence of Mutations in the Antimicrobial Target Genes Related to Levofloxacin, Clarithromycin, and Amoxicillin Resistance in Helicobacter pylori Isolates from Buenos Aires City.
Mutations in gyrA were found in 92.8% of levofloxacin-resistant isolates.
Genetic Determinants and Prediction of Antibiotic Resistance Phenotypes in Helicobacter pylori.
not associated with levofloxacin resistance
Mutations in the Antibiotic Target Genes Related to Clarithromycin, Metronidazole and Levofloxacin Resistance in Helicobacter pylori Strains from Children in China.
Mutations in gyrA are associated with levofloxacin resistance
Next-Generation Sequencing of the Whole Bacterial Genome for Tracking Molecular Insight into the Broad-Spectrum Antimicrobial Resistance of Helicobacter pylori Clinical Isolates from the Democratic Republic of Congo.
High Antibiotic Resistance of Helicobacter pylori and Its Associated Novel Gene Mutations among the Mongolian Population.
Phenotype and Molecular Detection of Clarithromycin and Levofloxacin Resistance in Helicobacter pylori Clinical Isolates in Beijing.
Using next-generation sequencing to analyze Helicobacter pylori clones with different levofloxacin resistances from a patient with eradication failure.
Single and double mutations in gyrA but not in gyrB are associated with low- and high-level fluoroquinolone resistance in Helicobacter pylori.
gyrA
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gyrA
Gemifloxacin can partially overcome quinolone resistance of H. pylori with gyrA mutation in Taiwan.
Helicobacter pylori gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3007052
Mutations of Helicobacter pylori associated with fluoroquinolone resistance in Korea.
Helicobacter pylori gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3007052
Genomic epidemiology and temperature dependency of hypermucoviscous Klebsiella pneumoniae in Japan.
Mutations associated with fluoroquinolone resistance in isolates MS5538 and MS5544.
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