ResLit - Antimicrobial Resistance Gene & Mutation Database

GenegyrA

Nucleotide ChangeGAT->GCC

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseResFinder DatabaseReslit

Overview

Resistance To: fluoroquinolones
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Phylogenomics of Globally Spread Clonal Groups 14 and 15 of Klebsiella pneumoniae.

Research Article

PMID 37098951 · 2023

Mutation Information

gyrA: c.GAT->GCC

Nucleotide Change: GAT->GCC
Confers Resistance To: fluoroquinolones
Validation Method: phylogenetic clustering
Source Database: Reslit

Rapid diagnosis of drug resistance to fluoroquinolones, amikacin, capreomycin, kanamycin and ethambutol using genotype MTBDRsl assay: a meta-analysis.

Review

PMID 23383320 · 2013

Mutations in gyrA gene confer resistance to fluoroquinolones.

Mutation Information

gyrA: p.D94A / c.GAT->GCC

Protein Change: D94A
Nucleotide Change: GAT->GCC
Organisms: Mycobacterium tuberculosis
Confers Resistance To: fluoroquinolones
Validation Method: hybridization of amplified DNA fragments from Mycobacterium tuberculosis to specific probes
Source Database: Reslit

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