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Browse Mutations mdtCV632I

GenemdtC

efflux pump component

Protein ChangeV632I

Nucleotide ChangeG1894A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delafloxacin, ciprofloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.

Research Article

PMID 37882542 · 2023

V632I in mdtC was the most common mutation in both DLX- and CIP-challenged strains.

Mutation Information

mdtC: p.V632I / c.G1894A

Protein Change: V632I
Nucleotide Change: G1894A
Organisms: Escherichia coli
Confers Resistance To: delafloxacinciprofloxacin
Validation Method: complementation assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
GitHub
Zenodo archive
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research