ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemarR

global regulator

Protein ChangeA53E

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Tigecycline
Papers: 1

Paper Information1

Tigecycline Nonsusceptibility Occurs Exclusively in Fluoroquinolone-Resistant Escherichia coli Clinical Isolates, Including the Major Multidrug-Resistant Lineages O25b:H4-ST131-H30R and O1-ST648.

PMID 27855067 · 2017

Mutations in marR contribute to tigecycline nonsusceptibility by overexpression of AcrAB-TolC.

Mutation Information

marR: p.A53E

Protein Change: A53E
Confers Resistance To: Tigecycline
Source Database: Reslit

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