ResLit - Antimicrobial Resistance Gene & Mutation Database

GenerpoB

Protein ChangeS509R

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Detection of multidrug resistance in Mycobacterium tuberculosis.

Research Article

PMID 17108078 · 2007

mutations in the 81-bp core region of rpoB are responsible for resistance in at least 96% of RIF-resistant M. tuberculosis isolates

Mutation Information

rpoB: p.S509R

Protein Change: S509R
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Validation Method: DNA sequencing
Source Database: Reslit

Lambda gpP-DnaB Helicase Sequestration and gpP-RpoB Associated Effects: On Screens for Auxotrophs, Selection for Rif(R), Toxicity, Mutagenicity, Plasmid Curing.

Research Article

PMID 27338450 · 2016

Mutations in rpoB gene lead to rifampicin resistance

Mutation Information

rpoB: p.S509R

Protein Change: S509R
Confers Resistance To: rifampicin
Validation Method: sequencing of rpoB gene from Rif R mutants; sequencing and phenotypic analysis
Source Database: Reslit

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