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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rdxAS18F

GenerdxA

oxygen-insensitive NADPH nitroreductase

Protein ChangeS18F

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss of function
Resistance To: Metronidazole
Organisms: Escherichia coli, Helicobacter pylori
Papers: 2

Paper Information2

1

Clarithromycin-Based Triple Therapy is Still Useful as an Initial Treatment for Helicobacter pylori Infection in the Dominican Republic.

PMID 28193745 · 2017

Mutation Information

Protein Change: S18F
Confers Resistance To: Metronidazole

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

2

Functional determination of site-mutations in rdxA involved in metronidazole resistance of Helicobacter pylori.

PMID 39100097 · 2024

Mutations in rdxA are associated with metronidazole resistance in H. pylori.

Mutation Information

Protein Change: S18F
Organisms: Escherichia coli, Helicobacter pylori
Confers Resistance To: Metronidazole
Effect on Function: loss of function
Source Database: Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research