ResLit - Antimicrobial Resistance Gene & Mutation Database

Nucleotide ChangeAGT->CTT

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Overview

Resistance To: ciprofloxacin, fluoroquinolones
Organisms: Shigella flexneri, Shigella sonnei
Papers: 3

Paper Information3

Phylogenomic Investigation of Increasing Fluoroquinolone Resistance among Belgian Cases of Shigellosis between 2013 and 2018 Indicates Both Travel-Related Imports and Domestic Circulation.

Research Article

PMID 33917583 · 2021

Mutations in gyrA are associated with ciprofloxacin resistance.

Mutation Information

gyrA: p.S83L / c.AGT->CTT

Protein Change: S83L
Nucleotide Change: AGT->CTT
Organisms: Shigella flexneri, Shigella sonnei
Confers Resistance To: ciprofloxacin
Validation Method: whole genome sequencing and phenotypic resistance testing
Source Database: Reslit

Fluoroquinolone-Resistant Enteric Bacteria in Sub-Saharan Africa: Clones, Implications and Research Needs.

Review

PMID 27148238 · 2016

Mutations in QRDR of gyrA and parC contribute to fluoroquinolone resistance.

Mutation Information

gyrA: p.S83L / c.AGT->CTT

Protein Change: S83L
Nucleotide Change: AGT->CTT
Confers Resistance To: fluoroquinolones
Validation Method: sequencing
Source Database: Reslit

Molecular characterization of fluoroquinolone and/or cephalosporin resistance in Shigella sonnei isolates from yaks.

Research Article

PMID 29879965 · 2018

Mutation Information

gyrA: c.AGT->CTT

Nucleotide Change: AGT->CTT
Organisms: Shigella sonnei
Confers Resistance To: fluoroquinolones
Validation Method: sequencing
Source Database: Reslit

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GenegyrA

Nucleotide ChangeAGT->CTT

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Overview

Resistance To: ciprofloxacin, fluoroquinolones
Organisms: Shigella flexneri, Shigella sonnei
Papers: 3

Paper Information3

Phylogenomic Investigation of Increasing Fluoroquinolone Resistance among Belgian Cases of Shigellosis between 2013 and 2018 Indicates Both Travel-Related Imports and Domestic Circulation.

Research Article

PMID 33917583 · 2021

Mutations in gyrA are associated with ciprofloxacin resistance.

Mutation Information

gyrA: p.S83L / c.AGT->CTT

Protein Change: S83L
Nucleotide Change: AGT->CTT
Organisms: Shigella flexneri, Shigella sonnei
Confers Resistance To: ciprofloxacin
Validation Method: whole genome sequencing and phenotypic resistance testing
Source Database: Reslit