Browse AMR Mutations

Mutation Information

Protein Change

K209E

Nucleotide Change

A625G

Organisms

Mycobacterium tuberculosis, Mycobacterium bovis

Confers Resistance To

pyrazinamide

Effect on Function

The mutation in the C-terminal tail of PanD causes POA resistance and prevents drug binding.

Validation Method

Susceptibility testing

Source Database

Reslit