ResLit - Antimicrobial Resistance Gene & Mutation Database

Nucleotide Change171, 176, 177, 178, 179, 180, 185, 186 or 195ins

Validation StatusCandidate

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Reslit

Overview

Resistance To: Trimethoprim/sulfamethoxazole
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

Antimicrobial resistance determinants and susceptibility profiles of pneumococcal isolates recovered in Trinidad and Tobago.

PMID 28818574 · 2017

One to two codon insertions within the folP gene result in an intermediate phenotype (MIC 1–2 mg/L) against SXT; when combined with the folA substitution I100L, they result in a resistant phenotype (MIC ≥ 4 mg/L).

Mutation Information

folP: c.171, 176, 177, 178, 179, 180, 185, 186 or 195ins

Nucleotide Change: 171, 176, 177, 178, 179, 180, 185, 186 or 195ins
Organisms: Streptococcus pneumoniae
Confers Resistance To: Trimethoprim/sulfamethoxazole
Source Database: Reslit

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