Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis.
all mutations are in the rpoB gene and confer resistance to rifampin
Rapid detection of rifampin resistance in Mycobacterium tuberculosis by Pyrosequencing technology.
Mutations in the rpoB gene are associated with rifampin resistance
Genetic determinants of drug-resistant tuberculosis among HIV-infected patients in Nigeria.
Rifabutin Resistance Associated with Double Mutations in rpoB Gene in Mycobacterium tuberculosis Isolates.
Mutations in rpoB gene are associated with rifabutin resistance
Antimicrobial Resistance in Mycobacterium tuberculosis Clinical Isolates from HIV-Positive and HIV-Negative Patients in Russia
Mutations in the rpoB Gene of Rifampin-Resistant Mycobacterium tuberculosis Strains Isolated Mostly in Asian Countries and Their Rapid Detection by Line Probe Assay.
Rapid detection of rpoB gene mutations in rifampin-resistant Mycobacterium tuberculosis isolates in shanghai by using the amplification refractory mutation system.
Mutation analysis of mycobacterial rpoB genes and rifampin resistance using recombinant Mycobacterium smegmatis.
All mutations were experimentally validated in this study.
Direct Detection of Rifampin and Isoniazid Resistance in Sputum Samples from Tuberculosis Patients by High-Resolution Melt Curve Analysis.
A Rapid Drug Resistance Genotyping Workflow for Mycobacterium tuberculosis, Using Targeted Isothermal Amplification and Nanopore Sequencing.
Mutations in rpoB confer resistance to rifampin
Molecular evidence for heterogeneity of the multiple-drug-resistant Mycobacterium tuberculosis population in Scotland (1990 to 1997).
Mutations in rpoB are associated with rifampin resistance.
Rapid detection of rifampin resistance in Mycobacterium tuberculosis isolates from India and Mexico by a molecular beacon assay.
Mutations in the rpoB gene confer rifampin resistance
Frequency and Type of Disputed rpoB Mutations in Mycobacterium tuberculosis Isolates from South Korea.
Disputed rpoB mutations causing low-level resistance to rifampin
The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing.
Mutations in rpoB were analyzed for their effect on rifampin resistance.
Mutations in rpoB and katG genes of multidrug resistant mycobacterium tuberculosis undetectable using genotyping diagnostic methods.
All mutations were identified through sequencing and are associated with rifampicin resistance.
Disputed rpoB Mutations in Mycobacterium tuberculosis and Tuberculosis Treatment Outcomes.
Mutations in the rpoB gene were associated with rifampin resistance in Mycobacterium tuberculosis.
Patterns of compensatory mutations in rpoA/B/C genes of multidrug resistant M. tuberculosis in Uganda.
Mutations in rpoB are associated with rifampicin resistance.
A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.
All mutations were confirmed by DNA sequencing.
Patterns of compensatory mutations in rpoA/B/C genes of multidrug resistant M. tuberculosis in Uganda.
Some mutations are classified as low-level resistance-conferring.
Characterization of Drug Resistance Patterns, Mutation Profiles and Prevalence of Mycobacterium tuberculosis in Shaoxing.
Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia.
associated with high-level rifampicin resistance
Comparative Evaluation of Sloppy Molecular Beacon and Dual-Labeled Probe Melting Temperature Assays to Identify Mutations in Mycobacterium tuberculosis Resulting in Rifampin, Fluoroquinolone and Aminoglycoside Resistance.
Reduced turn-around time for Mycobacterium tuberculosis drug susceptibility testing with a proportional agar microplate assay.
Pyrosequencing for rapid detection of tuberculosis resistance in clinical isolates and sputum samples from re-treatment pulmonary tuberculosis patients.
Correlation between genotypic and phenotypic testing for resistance to rifampin in Mycobacterium tuberculosis clinical isolates in Haiti: investigation of cases with discrepant susceptibility results.
all mutations are in the rpoB gene
Sequence analysis of the drug‑resistant rpoB gene in the Mycobacterium tuberculosis L‑form among patients with pneumoconiosis complicated by tuberculosis.
Profiling of rpoB mutations and MICs for rifampin and rifabutin in Mycobacterium tuberculosis.
mutations in rpoB are associated with resistance to rifampin and rifabutin
Distinguishing nontuberculous mycobacteria from multidrug-resistant Mycobacterium tuberculosis, China.
Successful Treatment with a High-dose Rifampin-containing Regimen for Pulmonary Tuberculosis with a Disputed rpoB Mutation.
Disputed rpoB mutation
Performance of an Xpert-based diagnostic algorithm for the rapid detection of drug-resistant tuberculosis among high-risk populations in a low-incidence setting.
Distribution and frequency of common mutations in rpoB gene of Mycobacterium tuberculosis detected by Xpert MTB/RIF and identification of residential areas of rifampicin resistant-TB cases: A first retrospective study from Mizoram, Northeast India.
Mutation detected in probe A region.
A rapid, accurate, and low-cost method for detecting Mycobacterium tuberculosis and its drug-resistant genes in pulmonary tuberculosis: Applications of MassARRAY DNA mass spectrometry.
Consistent with phenotypic results
Phenotypic drug susceptibility characterization and clinical outcomes of tuberculosis strains with A-probe mutation by GeneXpert MTB/RIF.
Mutations in rpoB gene associated with rifampicin resistance
A preliminary evaluation of targeted nanopore sequencing technology for the detection of Mycobacterium tuberculosis in bronchoalveolar lavage fluid specimens.
Primary multidrug-resistant Mycobacterium tuberculosis in 2 regions, Eastern Siberia, Russian Federation.
Mutations in the resistance-determining region of rpoB (codons 511–533) were present in only 79%.
Prevalence of rifampicin-resistant Mycobacterium tuberculosis among human-immunodeficiency-virus-seropositive patients and their treatment outcomes.
Mutations in the rpoB gene were associated with rifampicin resistance.
Absence of hybridization with the wild-type and mutant rpoB probes in the Genotype MTBDRplus assay detects 'disputed' rifampicin mutations.
Mutations in rpoB were identified in isolates that failed to hybridize to rpoB wild-type probes, and some of these mutations were 'disputed' as they did not consistently correlate with rifampicin resistance.
Mutations of rpoB, katG, inhA and ahp genes in rifampicin and isoniazid-resistant Mycobacterium tuberculosis in Kyrgyz Republic.
Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda.
Mutations in rpoB RRDR region associated with rifampicin resistance.
Interpretation of Discordant Rifampicin Susceptibility Test Results Obtained Using GeneXpert vs Phenotypic Drug Susceptibility Testing.
mutations in the rifampin resistance-determining region of the rpoB gene
Predicting rifampicin resistance in Mycobacterium tuberculosis using machine learning informed by protein structural and chemical features.
mutations in rpoB are associated with rifampicin resistance
Mycobacterium tuberculosis resistance prediction and lineage classification from genome sequencing: comparison of automated analysis tools.
Mutations in rpoB were identified in strains resistant to rifampicin.
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