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Browse Mutations rdxAA187V

GenerdxA

oxygen-insensitive NADPH nitroreductase

Protein ChangeA187V

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss of function
Resistance To: metronidazole
Organisms: Escherichia coli, Helicobacter pylori
Papers: 1

Paper Information1

1

Functional determination of site-mutations in rdxA involved in metronidazole resistance of Helicobacter pylori.

Research Article

PMID 39100097 · 2024

Mutations in rdxA are associated with metronidazole resistance in H. pylori.

Mutation Information

Protein Change: A187V
Organisms: Escherichia coli, Helicobacter pylori
Confers Resistance To: metronidazole
Effect on Function: loss of function
Validation Method: expression in E. coli DH5α and MTZ sensitivity test
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research