ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp2

penicillin-binding protein 2

Protein ChangeI415M

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Penicillin
Organisms: Treponema pallidum
Papers: 1

Paper Information1

Phylogenetic and genetic characterization of Treponema pallidum strains from syphilis patients in Japan by whole-genome sequence analysis from global perspectives.

PMID 33542273 · 2021

Most (9 of 11) of the TPA strains in China harbored pbp2 (TPANIC_0760) I415F or I415M mutation.

Mutation Information

pbp2: p.I415M

Protein Change: I415M
Organisms: Treponema pallidum
Confers Resistance To: Penicillin
Source Database: Reslit

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