Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis.
all mutations are in the rpoB gene and confer resistance to rifampin
Genetic evaluation of relationship between mutations in rpoB and resistance of Mycobacterium tuberculosis to rifampin.
Some mutations in the rpoB gene can reveal drug-resistant phenotype only in a specific genetic background of the host.
The beginning of the rpoB gene in addition to the rifampin resistance determination region might be needed for identifying rifampin/rifabutin cross-resistance in multidrug-resistant Mycobacterium tuberculosis isolates from Southern China.
Rapid detection of rpoB mutations in rifampin resistant M. tuberculosis from sputum samples by denaturing gradient gel electrophoresis.
mutations in rpoB gene associated with rifampin resistance
Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.
Mutations in the rpoB gene are responsible for rifampin resistance.
First Evaluation of GenoType MTBDRplus 2.0 Performed Directly on Respiratory Specimens in Central America.
Antimicrobial Resistance in Mycobacterium tuberculosis Clinical Isolates from HIV-Positive and HIV-Negative Patients in Russia
The Regulation of ManLAM-Related Gene Expression in Mycobacterium tuberculosis with Different Drug Resistance Profiles Following Isoniazid Treatment.
Use of the GenoType(R) MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda.
Mutations in the rpoB Gene of Rifampin-Resistant Mycobacterium tuberculosis Strains Isolated Mostly in Asian Countries and Their Rapid Detection by Line Probe Assay.
Rapid detection of rpoB gene mutations in rifampin-resistant Mycobacterium tuberculosis isolates in shanghai by using the amplification refractory mutation system.
Direct detection of rifampin-resistant mycobacterium tuberculosis in respiratory specimens by PCR-DNA sequencing.
Positive epistasis drives the acquisition of multidrug resistance.
Mutation analysis of mycobacterial rpoB genes and rifampin resistance using recombinant Mycobacterium smegmatis.
All mutations were experimentally validated in this study.
Genotypic characterization of drug resistant Mycobacterium tuberculosis in Quebec, 2002-2012.
most common mutation
Drug-resistant tuberculosis in Central Mozambique: the role of a rapid genotypic susceptibility testing.
Assessment of a 96-Well Plate Assay of Quantitative Drug Susceptibility Testing for Mycobacterium Tuberculosis Complex in China.
Direct Detection of Rifampin and Isoniazid Resistance in Sputum Samples from Tuberculosis Patients by High-Resolution Melt Curve Analysis.
In vitro and in vivo fitness costs associated with Mycobacterium tuberculosis RpoB mutation H526D.
The mutation H526D in the rpoB gene was associated with reduced Mtb virulence and delayed resuscitation from nutrient starvation.
Combination of commercially available molecular assays and culture based methods in diagnosis of tuberculosis and drug resistant tuberculosis.
Among the five isolates that were resistant to RMP various mutations of the rpoB gene were detected. The types of mutations were similar to those found in a previous study from Greek patients affecting most commonly codons 531 and 526.
Genotypic Distribution and a Potential Diagnostic Assay of Multidrug-Resistant Tuberculosis in Northern Thailand.
Mutations associated with resistance to rifampicin and isoniazid identified in strains of the Mycobacterium tuberculosis complex by GenoType MTBDRplus in Panama, 2015-2021.
Use of real-time PCR and fluorimetry for rapid detection of rifampin and isoniazid resistance-associated mutations in Mycobacterium tuberculosis.
Characterization of mutations in the rpoB gene associated with rifampin resistance in Rhodococcus equi isolated from foals.
Mutations in the rpoB gene are associated with rifampin resistance in Rhodococcus equi.
Physiological cost of rifampin resistance induced in vitro in Mycobacterium tuberculosis.
New real-time PCR able to detect in a single tube multiple rifampin resistance mutations and high-level isoniazid resistance mutations in Mycobacterium tuberculosis.
Mutations in rpoB gene associated with rifampin resistance
Multidrug-resistant tuberculosis detection, Latvia.
Mutations detected by line probe assay for rpoB gene.
Evaluation of the TB-Biochip oligonucleotide microarray system for rapid detection of rifampin resistance in Mycobacterium tuberculosis.
Characterization of RPO B gene for detection of rifampicin drug resistance by SSCP and sequence analysis.
Mutations in the rpoB gene were associated with rifampicin resistance.
High-resolution melting curve analysis for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates.
Mutations in rpoB gene are associated with rifampin resistance.
Use of multiplex allele-specific polymerase chain reaction (MAS-PCR) to detect multidrug-resistant tuberculosis in Panama.
Detected in 53/67 isolates
Increased survival of antibiotic-resistant Escherichia coli inside macrophages.
The mutation was found to confer resistance to rifampin.
The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing.
Mutations in rpoB were analyzed for their effect on rifampin resistance.
Mutations in rpoB and katG genes of multidrug resistant mycobacterium tuberculosis undetectable using genotyping diagnostic methods.
All mutations were identified through sequencing and are associated with rifampicin resistance.
Molecular epidemiology of Mycobacterium tuberculosis complex in the Volta Region of Ghana.
Patterns of compensatory mutations in rpoA/B/C genes of multidrug resistant M. tuberculosis in Uganda.
Mutations in rpoB are associated with rifampicin resistance.
Patterns of compensatory mutations in rpoA/B/C genes of multidrug resistant M. tuberculosis in Uganda.
Some mutations are classified as low-level resistance-conferring.
A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.
All mutations were confirmed by DNA sequencing.
Assessment of the genotype MTBDRplus assay for rifampin and isoniazid resistance detection on sputum samples in Cote d'Ivoire.
Defining multidrug-resistant tuberculosis: correlating GenoType MTBDRplus assay results with minimum inhibitory concentrations.
mutations in the rpoB gene are associated with rifampicin resistance
Mutations conferring resistance to first- and second-line drugs in multidrug-resistant Mycobacterium tuberculosis clinical isolates in southeast Mexico.
Comparative Evaluation of Sloppy Molecular Beacon and Dual-Labeled Probe Melting Temperature Assays to Identify Mutations in Mycobacterium tuberculosis Resulting in Rifampin, Fluoroquinolone and Aminoglycoside Resistance.
Molecular profiling of drug resistant isolates of Mycobacterium tuberculosis in the state of Santa Catarina, southern Brazil.
Mutations in rpoB are associated with rifampicin resistance.
Potential for adaptation overrides cost of resistance.
Detection of multidrug-resistant Mycobacterium tuberculosis strains isolated in Brazil using a multimarker genetic assay for katG and rpoB genes.
associated with rifampicin resistance
Prevalence, risk and genetic characteristics of drug-resistant tuberculosis in a tertiary care tuberculosis hospital in China.
Evaluation of the AID TB resistance line probe assay for rapid detection of genetic alterations associated with drug resistance in Mycobacterium tuberculosis strains.
Rifampicin mono-resistant tuberculosis in France: a 2005-2010 retrospective cohort analysis.
Mutations identified in rpoB were associated with rifampicin resistance.
Pyrosequencing for rapid detection of tuberculosis resistance in clinical isolates and sputum samples from re-treatment pulmonary tuberculosis patients.
Comparison of Xpert MTB/RIF with line probe assay for detection of rifampin-monoresistant Mycobacterium tuberculosis.
Correlation between genotypic and phenotypic testing for resistance to rifampin in Mycobacterium tuberculosis clinical isolates in Haiti: investigation of cases with discrepant susceptibility results.
all mutations are in the rpoB gene
Sequence analysis for detection of drug resistance in Mycobacterium tuberculosis complex isolates from the Central Region of Cameroon.
mutated in RIF-resistant isolates
Profiling of rpoB mutations and MICs for rifampin and rifabutin in Mycobacterium tuberculosis.
mutations in rpoB are associated with resistance to rifampin and rifabutin
Mutations of rpob Gene Associated with Rifampin Resistance among Mycobacterium Tuberculosis Isolated in Tuberculosis Regional Reference Laboratory in Northeast of Iran during 2015-2016.
Phenotypic and genotypic drug sensitivity of Mycobacterium tuberculosis complex isolated from South Omo Zone, Southern Ethiopia.
Multidrug-resistant tuberculosis in panama is driven by clonal expansion of a multidrug-resistant Mycobacterium tuberculosis strain related to the KZN extensively drug-resistant M. tuberculosis strain from South Africa.
Ultrasensitive Detection of Multidrug-Resistant Mycobacterium tuberculosis Using SuperSelective Primer-Based Real-Time PCR Assays.
A rapid, accurate, and low-cost method for detecting Mycobacterium tuberculosis and its drug-resistant genes in pulmonary tuberculosis: Applications of MassARRAY DNA mass spectrometry.
Poor correlation with phenotype
Mutation patterns of resistance genes for macrolides, aminoglycosides, and rifampicin in non-tuberculous mycobacteria isolates from Kenya.
Prevalence of Mycobacterium tuberculosis mutations associated with isoniazid and rifampicin resistance: A systematic review and meta-analysis.
Molecular Analysis of Anti-Tuberculosis Drug Resistance of Mycobacterium tuberculosis Isolated in the Republic of Korea.
A simple, rapid and economic method for detecting multidrug-resistant tuberculosis.
Detected in 80 isolates
Effect of mutation and genetic background on drug resistance in Mycobacterium tuberculosis.
RpoB mutations are associated with rifampin resistance
Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.
Mutations in rpoB were identified in rifampin-resistant mutants.
Comparison of line probe assay with liquid culture for rapid detection of multi-drug resistance in Mycobacterium tuberculosis.
Mutations in rpoB gene confer resistance to rifampicin.
Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis.
Mutations in rpoB confer resistance to rifampicin
Correlation between the BACTEC MGIT 960 culture system with Genotype MTBDRplus and TB-SPRINT in multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil.
Prevalence of rifampicin-resistant Mycobacterium tuberculosis among human-immunodeficiency-virus-seropositive patients and their treatment outcomes.
Mutations in the rpoB gene were associated with rifampicin resistance.
Rapid Microarray-Based Detection of Rifampin, Isoniazid, and Fluoroquinolone Resistance in Mycobacterium tuberculosis by Use of a Single Cartridge.
Mutations in rpoB, katG, and gyrA were analyzed for their association with resistance to rifampin, isoniazid, and fluoroquinolones.
Altered Mycobacterium tuberculosis Cell Wall Metabolism and Physiology Associated With RpoB Mutation H526D.
Mutations of rpoB, katG, inhA and ahp genes in rifampicin and isoniazid-resistant Mycobacterium tuberculosis in Kyrgyz Republic.
Validation of the FluoroType MTBDR Assay for Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Complex Isolates.
Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda.
Mutations in rpoB RRDR region associated with rifampicin resistance.
Frequency of genomic mutations mediating resistance of Mycobacterium tuberculosis isolates to rifampicin in Northern Morocco.
Mutations in the rpoB gene were identified as the primary cause of rifampicin resistance in Mycobacterium tuberculosis isolates.
Pervasive genotype-by-environment interactions shape the fitness effects of antibiotic resistance mutations.
All mutations are in the rpoB gene, which encodes the beta subunit of RNA polymerase.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research