Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Activities of trovafloxacin compared with those of other fluoroquinolones against purified topoisomerases and gyrA and grlA mutants of Staphylococcus aureus.
Research Article
mutation in gyrA gene
Novel approach for comparing the abilities of quinolones to restrict the emergence of resistant mutants during quinolone exposure.
Research Article
Mutations in gyrA were identified as key determinants of quinolone resistance in E. coli.
Comparison of the metabolic activities of four wild-type Clostridium perfringens strains with their gatifloxacin-selected resistant mutants.
Research Article
Mutation in DNA gyrase gene
Repression of invasion genes and decreased invasion in a high-level fluoroquinolone-resistant Salmonella typhimurium mutant.
Research Article
Mutations in QRDR of gyrA contribute to fluoroquinolone resistance
Gatifloxacin activity against quinolone-resistant gyrase: allele-specific enhancement of bacteriostatic and bactericidal activities by the C-8-methoxy group.
Research Article
Use of an in vitro pharmacodynamic model to derive a moxifloxacin regimen that optimizes kill of Yersinia pestis and prevents emergence of resistance.
Research Article
Single point mutation in gyrA associated with increased moxifloxacin MIC.
Time-Resolved Tracking of Mutations Reveals Diverse Allele Dynamics during Escherichia coli Antimicrobial Adaptive Evolution to Single Drugs and Drug Pairs.
Research Article
Suppression of gyrase-mediated resistance by C7 aryl fluoroquinolones.
Research Article
Mutations in gyrA were found to confer resistance to fluoroquinolones.
Mutations were identified in E. coli strains selected under pressure of ciprofloxacin and Cip-DNP.
Could traces of fluoroquinolones in food induce ciprofloxacin resistance in Escherichia coli and Klebsiella pneumoniae? An in vivo study in Galleria mellonella with important implications for maximum residue limits in food.
Research Article
Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding.
Research Article
Mutations in GyrA contribute to fluoroquinolone resistance through cross-linking mechanisms.
Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.
Research Article
G81D mutation confers resistance to ciprofloxacin only. If G81D and D82G are present simultaneously, there is also nalidixic acid resistance
Escherichia coli gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003294
gyrA
Novel gyrA point mutation in a strain of Escherichia coli resistant to fluoroquinolones but not to nalidixic acid.
Research Article
G81D mutation confers resistance to ciprofloxacin only. If G81D and D82G are present simultaneously, there is also nalidixic acid resistance
Comparative studies of mutations in animal isolates and experimental in vitro- and in vivo-selected mutants of Salmonella spp. suggest a counterselection of highly fluoroquinolone-resistant strains in the field.
Research Article
Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance.
Research Article
Geographically dependent distribution of gyrA gene mutations at codons 83 and 87 in Salmonella Hadar, and a novel codon 81 Gly to His mutation in Salmonella Enteritidis.
Research Article
High-level resistance to fluoroquinolones and cephalosporins in Burkholderia pseudomallei and closely related species.
Research Article
gyrA
A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas aeruginosa.
Research Article
gyrA
Mechanisms of quinolone resistance in Escherichia coli and Salmonella: recent developments.
Review
gyrA
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