ResLit - Antimicrobial Resistance Gene & Mutation Database

Generrl

23S rRNA

Nucleotide ChangeT2500A

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseResFinder Database

Overview

Mechanism: Target modification, single resistance variant
Resistance To: linezolid, pleuromutilins
Organisms: Staphylococcus aureus, Thermus thermophilus
Papers: 2

Paper Information2

Linezolid resistance in sequential Staphylococcus aureus isolates associated with a T2500A mutation in the 23S rRNA gene and loss of a single copy of rRNA.

Research Article

PMID 15216466 · 2004

Mutation Information

rrl: c.T2500A

Nucleotide Change: T2500A
Organisms: Staphylococcus aureus
Confers Resistance To: linezolid
Effect on Function: Target modification
Source Database: ResFinder Database

Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus.

Research Article

PMID 32526926 · 2020

Thermus thermophilus 23s rRNA conferring resistance to pleuromutilin antibiotics; CARD accession: CARD:3005083

Mutation Information

rrl: c.T2500A

Nucleotide Change: T2500A
Organisms: Thermus thermophilus
Confers Resistance To: pleuromutilins
Effect on Function: single resistance variant
Source Database: Card Database

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