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Browse Mutations rpoBA1085V

GenerpoB

Protein ChangeA1085V

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, DNA-directed RNA polymerase subunit beta RpoB
Resistance To: daptomycin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Genetic changes that correlate with reduced susceptibility to daptomycin in Staphylococcus aureus.

Research Article

PMID 16723576 · 2006

Staphylococcus aureus rpoB mutants conferring resistance to daptomycin; CARD accession: CARD:3003287

Mutation Information

Protein Change: A1085V
Organisms: Staphylococcus aureus
Confers Resistance To: daptomycin
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
GitHub
Zenodo archive
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research