ResLit - Antimicrobial Resistance Gene & Mutation Database

GenebaeS

two-component system histidine kinase

Protein ChangeT175P

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: two-component system sensor histidine kinase BaeS
Resistance To: aztreonam, temocillin, ticarcillin
Organisms: Enterobacter asburiae, Enterobacter cloacae, Escherichia coli
Papers: 2

Paper Information2

Temocillin Resistance in the Enterobacter cloacae Complex Is Conferred by a Single Point Mutation in BaeS, Leading to Overexpression of the AcrD Efflux Pump.

Research Article

PMID 37195180 · 2023

baeS

Mutation Information

baeS: p.T175P

Protein Change: T175P
Organisms: Enterobacter asburiae, Enterobacter cloacae
Confers Resistance To: aztreonamtemocillinticarcillin
Effect on Function: two-component system sensor histidine kinase BaeS
Source Database: Reference Gene Catalog

Impact of the phenotypic expression of temocillin resistance in Escherichia coli on temocillin efficacy in a murine peritonitis model.

Research Article

PMID 38501355 · 2024

baeS

Mutation Information

baeS: p.T175P

Protein Change: T175P
Organisms: Escherichia coli
Confers Resistance To: temocillin
Effect on Function: two-component system sensor histidine kinase BaeS
Source Database: Reference Gene Catalog

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