ResLit - Antimicrobial Resistance Gene & Mutation Database

GenerpoB

Protein ChangeQ489K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Rifampin|Rifaximin, RIF
Organisms: Clostridium difficile
Papers: 2

Paper Information2

Coinfection and Emergence of Rifamycin Resistance during a Recurrent Clostridium difficile Infection.

PMID 27558181 · 2016

Mutation Information

rpoB: p.Q489K

Protein Change: Q489K
Organisms: Clostridium difficile
Confers Resistance To: Rifampin|Rifaximin
Source Database: Reslit

Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.

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