GeneparE
Protein ChangeS458A
Validation StatusConfirmed2+ DBs
Databases
ResFinderReslit
Overview
- Mechanism
- Target modification
- Resistance To
- fluoroquinolones, Nalidixic acid,Ciprofloxacin
- Organisms
- Haemophilus influenzae, Escherichia coli
- Papers
- 3
Paper Information3
1
Bactericidal activity of besifloxacin against staphylococci, Streptococcus pneumoniae and Haemophilus influenzae.
Mutation Information
- Protein Change
- S458A
- Organisms
- Haemophilus influenzae
- Confers Resistance To
- fluoroquinolones
- Source Database
- Reslit
2
Avoiding perforation during endodontic access.
Unknown phenotype if S458T or S458A occur alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Mutation Information
- Protein Change
- S458A
- Organisms
- Escherichia coli
- Confers Resistance To
- Nalidixic acid,Ciprofloxacin
- Effect on Function
- Target modification
- Source Database
- ResFinder
3
Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.
Unknown phenotype if S458T or S458A occur alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Mutation Information
- Protein Change
- S458A
- Organisms
- Escherichia coli
- Confers Resistance To
- Nalidixic acid,Ciprofloxacin
- Effect on Function
- Target modification
- Source Database
- ResFinder
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