Overview
- Mechanism
- Target modification
- Resistance To
- rifampin, rifampin|rifabutin|rifapentine|sorangicin A, rifampicin|rifabutin, Rifampicin
- Organisms
- Mycobacterium tuberculosis, Escherichia coli
- Papers
- 6
Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis.
all mutations are in the rpoB gene and confer resistance to rifampin
Mutation Information
- Protein Change
- H526Y
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- rifampin
- Source Database
- Reslit
Multiple rpoB mutants of Mycobacterium tuberculosis and second-order selection.
Mutations in rpoB are associated with rifampin resistance in M. tuberculosis.
Mutation Information
- Protein Change
- H526Y
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- rifampin
- Source Database
- Reslit
Cross-resistance of Escherichia coli RNA polymerases conferring rifampin resistance to different antibiotics.
Mutations in the rpoB gene encoding the beta subunit of RNA polymerase confer resistance to rifampin and related antibiotics.
Mutation Information
- Protein Change
- H526Y
- Organisms
- Escherichia coli
- Confers Resistance To
- rifampin|rifabutin|rifapentine|sorangicin A
- Source Database
- Reslit
Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency.
Mutations in the rpoB gene were identified through sequencing of gene fragments.
Mutation Information
- Protein Change
- H526Y
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- rifampicin|rifabutin
- Source Database
- Reslit
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
Previously reported
Mutation Information
- Protein Change
- H526Y
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- rifampin
- Source Database
- Reslit
Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance.
Mutation Information
- Protein Change
- H526Y
- Organisms
- Escherichia coli
- Confers Resistance To
- Rifampicin
- Effect on Function
- Target modification
- Source Database
- ResFinder
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