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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rpoBL511Q

GenerpoB

Protein ChangeL511Q

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoB
Resistance To: Rifampicin, RIFAMPIN
Organisms: Mycobacterium tuberculosis, Shigella sonnei
Papers: 2

Paper Information2

1

A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.

PMID 41420205 · 2025

All mutations were confirmed by DNA sequencing.

Mutation Information

Protein Change: L511Q
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Rifampicin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

2

Compensatory evolution in rifampin-resistant Escherichia coli.

PMID 11102350 · 2000

rpoB

Mutation Information

Protein Change: L511Q
Organisms: Shigella sonnei
Confers Resistance To: RIFAMPIN
Effect on Function: DNA-directed RNA polymerase subunit beta RpoB
Source Database: Reference Gene Catalog

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research