Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
In vitro and in vivo profiles of ACH-702, an isothiazoloquinolone, against bacterial pathogens.
Mutations in grlA (Ser80Phe, Ser80Tyr, Ser80Phe Glu84Lys) lead to fluoroquinolone resistance.
Genomic and Long-Term Transcriptomic Imprints Related to the Daptomycin Mechanism of Action Occurring in Daptomycin- and Methicillin-Resistant Staphylococcus aureus Under Daptomycin Exposure.
Mutations in grlA gene leading to reduced susceptibility to fluoroquinolones
Clonal Lineages, Antimicrobial Resistance, and PVL Carriage of Staphylococcus aureus Associated to Skin and Soft-Tissue Infections from Ambulatory Patients in Portugal.
A platform for detecting cross-resistance in antibacterial drug discovery.
Epidemiology of the Staphylococcus aureus CA-MRSA USA300 in Belgium.
Activities of trovafloxacin compared with those of other fluoroquinolones against purified topoisomerases and gyrA and grlA mutants of Staphylococcus aureus.
Pharmacodynamic Modeling of Ciprofloxacin Resistance in Staphylococcus aureus.
Evolution of Ciprofloxacin-Resistant Staphylococcus aureus in In Vitro Pharmacokinetic Environments
Mutation detected in grlA QRDR
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus.
A novel approach to associate genes and mutations with drug resistance phenotypes by comparative analysis of fully sequenced bacterial strains
Antimicrobial Resistance and Virulence of Methicillin-Resistant Staphylococcus aureus from Human, Chicken and Environmental Samples within Live Bird Markets in Three Nigerian Cities.
Genomic analysis of Staphylococcus aureus isolates from bacteremia reveals genetic features associated with the COVID-19 pandemic.
Skin Infections Caused by Panton-Valentine Leukocidin and Methicillin-Susceptible Staphylococcus aureus in Child, Japan.
Use of a three-dimensional microarray system for detection of levofloxacin resistance and the mecA gene in Staphylococcus aureus.
Virulence Determinants in Staphylococcus aureus Clones Causing Osteomyelitis in Italy.
Dissecting the genetic features and evolution of Staphylococcus aureus sequence type 88: a global perspective.
Present in most quinolone-resistant ST88 strains.
Transmission and microevolution of USA300 MRSA in U.S. households: evidence from whole-genome sequencing.
Evolution and Global Transmission of a Multidrug-Resistant, Community-Associated Methicillin-Resistant Staphylococcus aureus Lineage from the Indian Subcontinent.
The grlA S80Y mutation was fixed in ST772-A2 and -A3.
In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor.
Genomic Diversity of Methicillin-Resistant Staphylococcus aureus CC398 Isolates Collected from Diseased Swine in the German National Resistance Monitoring Program GERM-Vet from 2007 to 2019.
Fluoroquinolone resistance does not facilitate phage Φ13 integration or excision in Staphylococcus aureus.
Genetic Determinants in MRSA Carriage and Their Association with Decolonization Outcome.
Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates.
Susceptibility and resistance genes to fluoroquinolones in methicillin-resistant Staphylococcus aureus isolated in 2002.
Characterization of gyrA, gyrB, grlA and grlB mutations in fluoroquinolone-resistant clinical isolates of Staphylococcus aureus.
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