Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Various penA mutations together with mtrR, porB and ponA mutations in Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime or ceftriaxone.
ponA mutations including Leu-421→Pro are associated with reduced susceptibility to cefixime and ceftriaxone.
The antimicrobial resistance landscape of Neisseria gonorrhoeae in New Zealand from November 2018 to March 2019 and the role of sexual orientation in transmission.
Mutation in ponA contributes to reduced susceptibility to ceftriaxone and cefixime.
WGS to predict antibiotic MICs for Neisseria gonorrhoeae.
Genomic surveillance of Neisseria gonorrhoeae in the Philippines, 2013-2014.
Reliability of Genetic Alterations in Predicting Ceftriaxone Resistance in Neisseria gonorrhoeae Globally.
Global concerns, local challenges: the alarming spread of FC428-related gonococcal strains in Nanchang City, 2021.
single nucleotide polymorphism
Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains.
The use of cephalosporins for gonorrhea: the impending problem of resistance.
The L421P substitution in ponA may contribute to ceftriaxone resistance.
Molecular Typing of Neisseria gonorrhoeae Clinical Isolates in Russia, 2018-2019: A Link Between penA Alleles and NG-MAST Types.
Hydrogel Droplet Microarray for Genotyping Antimicrobial Resistance Determinants in Neisseria gonorrhoeae Isolates.
Neisseria gonorrhoeae FC428 Subclone, Vietnam, 2019-2020.
associated with penicillin resistance
Genetic identification of mutations and MLST types associated with decreased susceptibility to ceftriaxone in Neisseria gonorrhoeae.
Mutation in ponA is associated with ceftriaxone resistance.
Molecular Assay for Detection of Genetic Markers Associated with Decreased Susceptibility to Cephalosporins in Neisseria gonorrhoeae.
Neisseria gonorrhoeae Resistant to Ceftriaxone and Cefixime, Argentina.
Amino acid substitution in the ponA gene
Equations To Predict Antimicrobial MICs in Neisseria gonorrhoeae Using Molecular Antimicrobial Resistance Determinants.
Antimicrobial resistance genetic factor identification from whole-genome sequence data using deep feature selection.
Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution.
Antimicrobial resistance and heterogeneity of Neisseria gonorrhoeae isolated from patients attending sexually transmitted infection clinics in Lusaka, Zambia.
Antibiotic Targets in Gonococcal Cell Wall Metabolism.
Antimicrobial resistance prediction and phylogenetic analysis of Neisseria gonorrhoeae isolates using the Oxford Nanopore MinION sequencer.
Identification of Internationally Disseminated Ceftriaxone-Resistant Neisseria gonorrhoeae Strain FC428, China
PonA1 variant
Dissemination of Neisseria gonorrhoeae with decreased susceptibility to extended-spectrum cephalosporins in Southern China, 2021: a genome-wide surveillance from 20 cities.
Phenotypic and genotypic characterization of Neisseria gonorrhoeae isolates from Yaoundé, Cameroon, 2019 to 2020.
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future.
Genomic epidemiology and antimicrobial resistance of Neisseria gonorrhoeae in New Zealand.
Phylogeny and antimicrobial resistance in Neisseria gonorrhoeae isolates from Rio de Janeiro, Brazil.
Whole-genome sequencing reveals transmission of gonococcal antibiotic resistance among men who have sex with men: an observational study.
Cephalosporin-Resistant Neisseria gonorrhoeae Clone, China
Molecular Algorithms Accurately Predict Decreased Susceptibility to Ceftriaxone in Neisseria gonorrhoeae.
Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants of Neisseria gonorrhoeae.
mutations in ponA contribute to resistance by reducing penicillin binding
Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae.
ponA
Mediates transformation of intermediate-level penicillin-resistant transformants to high-level penicillin resistance
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