Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes clinical isolates with alterations in GyrA and ParC proteins.
mutations in gyrA are associated with fluoroquinolone resistance
Deciphering the Resistome of the Widespread Pseudomonas aeruginosa Sequence Type 175 International High-Risk Clone through Whole-Genome Sequencing.
associated with fluoroquinolone resistance
Ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from pigs to humans, Taiwan.
Development and validation of a diagnostic DNA microarray to detect quinolone-resistant Escherichia coli among clinical isolates.
Single nucleotide exchange at position 83
Cephalosporin and ciprofloxacin resistance in Salmonella, Taiwan.
Mutations in gyrA and parC contribute to ciprofloxacin resistance
Characterization of isolates of Salmonella enterica serovar typhimurium displaying high-level fluoroquinolone resistance in Japan.
Human Salmonella and concurrent decreased susceptibility to quinolones and extended-spectrum cephalosporins.
Antimicrobial resistance types and genes in Salmonella enterica infantis isolates from retail raw chicken meat and broiler chickens on farms.
Mutations in the quinolone resistance-determining region of gyrA contribute to nalidixic acid resistance.
Analysis of ciprofloxacin-resistant Salmonella strains from swine, chicken, and their carcasses in Taiwan and detection of parC resistance mutations by a mismatch amplification mutation assay PCR.
Comparison of the prevalences and antimicrobial resistances of Escherichia coli isolates from different retail meats in the United States, 2002 to 2008.
Genetic markers of widespread extensively drug-resistant Pseudomonas aeruginosa high-risk clones.
Mutations in gyrA contribute to high-level fluoroquinolone resistance.
Predicting antimicrobial susceptibilities for Escherichia coli and Klebsiella pneumoniae isolates using whole genomic sequence data.
associated with ciprofloxacin resistance
The clinical and microbiological characteristics of enteric fever in Cambodia, 2008-2015.
Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.
A Multidrug-resistant Monophasic Salmonella Typhimurium Co-harboring mcr-1, fosA3, bla (CTX-M-14) in a Transferable IncHI2 Plasmid from a Healthy Catering Worker in China.
Detected in the strain YZU1189
A Multifactorial Approach for Surveillance of Shigella spp. and Entero-Invasive Escherichia coli Is Important for Detecting (Inter)national Clusters.
Novel Molecular Markers Linked to Pseudomonas aeruginosa Epidemic High-Risk Clones.
associated with high-risk clones
Extended-Spectrum β-Lactamases in Human Isolates of Multidrug-Resistant Non-typhoidal Salmonella enterica.
associated with quinolone resistance
Genome-based characterization of Escherichia coli causing bloodstream infection through next-generation sequencing.
Emerging carbapenem-resistant Klebsiella pneumoniae sequence type 16 causing multiple outbreaks in a tertiary hospital in southern Vietnam.
Mutations in gyrA contribute to fluoroquinolone resistance.
Phylogenomic Investigation of Increasing Fluoroquinolone Resistance among Belgian Cases of Shigellosis between 2013 and 2018 Indicates Both Travel-Related Imports and Domestic Circulation.
Mutations in gyrA are associated with ciprofloxacin resistance.
Characterization of Antimicrobial Resistance Mechanisms in Clinical Isolates of Pseudomonas aeruginosa from a Cystic Fibrosis Patient
A global resource for genomic predictions of antimicrobial resistance and surveillance of Salmonella Typhi at pathogenwatch.
Shared and Unique Evolutionary Trajectories to Ciprofloxacin Resistance in Gram-Negative Bacterial Pathogens.
Mutations in gyrA are responsible for ciprofloxacin resistance in E. coli, A. baumannii, and P. aeruginosa.
Characterization of antibiotic resistance in Escherichia coli isolates from Black-headed gulls (Larus ridibundus) present in the city of Novi Sad, Serbia.
Identification of CTX-M Type ESBL E. coli from Sheep and Their Abattoir Environment Using Whole-Genome Sequencing.
The Pheno- and Genotypic Characterization of Porcine Escherichia coli Isolates.
Antimicrobial Resistance and Virulence Characteristics of Klebsiella pneumoniae Isolates in Kenya by Whole-Genome Sequencing.
Occurrence and Genomic Characterization of Clone ST1193 Clonotype 14-64 in Uncomplicated Urinary Tract Infections Caused by Escherichia coli in Spain.
Genomic surveillance of Pseudomonas aeruginosa in the Philippines, 2013-2014.
International High-Risk Clones Among Extended-Spectrum β-Lactamase-Producing Escherichia coli in Dhaka, Bangladesh.
Emergence of novel strains of Shigella flexneri associated with sexual transmission in adult men in England, 2019-2020.
Phylogenetic Analysis Reveals Distinct Evolutionary Trajectories of the Fluoroquinolones-Resistant Escherichia coli ST1193 From Fuzhou, China.
Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars.
Common mutation in S. Typhi and other Salmonella serovars.
Mutations in gyrA are common in quinolone-resistant Salmonella isolates.
Whole-Genome Sequencing-Based Antimicrobial Resistance Characterization and Phylogenomic Investigation of 19 Multidrug-Resistant and Extended-Spectrum Beta-Lactamase-Positive Escherichia coli Strains Collected From Hospital Patients in Benin in 2019.
Acquired resistome and plasmid sequencing of mcr-1 carrying MDR Enterobacteriaceae from poultry and their relationship to STs associated with humans.
Diversity in the Characteristics of Klebsiella pneumoniae ST101 of Human, Environmental, and Animal Origin.
Genetic diversity and multidrug resistance of phylogenic groups B2 and D in InPEC and ExPEC isolated from chickens in Central China.
Mutations in gyrA confer resistance to quinolones.
Role of Efflux in Antibiotic Resistance of Achromobacter xylosoxidans and Achromobacter insuavis Isolates From Patients With Cystic Fibrosis.
Mutations in QRDR of gyrA associated with ciprofloxacin resistance.
Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth.
Genome and antibiotic resistance characteristics of Shigella clinical isolates in Fujian Province, Southeast China, 2005-2019.
Mutations in gyrA and parC contribute to quinolone resistance.
Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81.
Mutations in the QRDR of gyrA contribute to fluoroquinolone resistance.
Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing.
Pandemic one health clones of Escherichia coli and Klebsiella pneumoniae producing CTX-M-14, CTX-M-27, CTX-M-55 and CTX-M-65 ESβLs among companion animals in northern Ecuador.
Molecular epidemiology of Salmonella Enteritidis in humans and animals in Spain.
Effects of different mechanisms on antimicrobial resistance in Pseudomonas aeruginosa: a strategic system for evaluating antibiotics against gram-negative bacteria.
Antimicrobial Resistance and Genomic Characterization of Salmonella Isolated from Pigeons in China.
Mutations in quinolone resistance-determining region
A global atlas and drivers of antimicrobial resistance in Salmonella during 1900-2023.
Unveiling the Genetic Diversity and Antimicrobial Resistance Profiles of Salmonella Population From 2016 to 2020 in Thai Canal Water.
Double amino acid substitutions in both positions of GyrA (S83F, D87N) and ParC (T57S, S80I) were observed in only S. Kentucky ST198 strains.
Prevalence and genetic characteristics of antimicrobial-resistant Escherichia coli in wild birds in Japan.
Resistance Mechanisms of Fluoroquinolone in Escherichia coli Isolated from Taihe Black-Boned Silky Fowl Exhibiting Abnormally Slow Fluoroquinolone Metabolism in Jiangxi, China.
The GyrA-S83Q mutation was reported as novel in this study.
Genomic characterisation of multidrug-resistant Salmonella enterica serovar Kentucky ST198 isolates from various sources in Algeria, North Africa.
Mutation in the quinolone-resistance-determining region of the gyrA gene
Prevalence and genetic basis of extended-spectrum β-lactamase-producing Escherichia coli carriage in broiler farms in the United Arab Emirates.
Multilocus variable-number tandem-repeat analysis, pulsed-field gel electrophoresis, and antimicrobial susceptibility patterns in discrimination of sporadic and outbreak-related strains of Yersinia enterocolitica.
Mutations in gyrA were associated with resistance to nalidixic acid and reduced susceptibility to ciprofloxacin.
Detection of Decreased Fluoroquinolone Susceptibility in Salmonellas and Validation of Nalidixic Acid Screening Test
Use of a LightCycler gyrA mutation assay for rapid identification of mutations conferring decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates.
Mutations in gyrA confer decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates.
High-level fluoroquinolone resistance in ophthalmic clinical isolates belonging to the species Corynebacterium macginleyi.
Mutations in the QRDRs of the gyrA gene were responsible for fluoroquinolone resistance in Corynebacterium macginleyi.
Ciprofloxacin-resistant Salmonella Kentucky in travelers.
Mutations in gyrA lead to ciprofloxacin resistance.
Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones.
Double amino acid substitutions in gyrA
Novel approach for comparing the abilities of quinolones to restrict the emergence of resistant mutants during quinolone exposure.
Mutations in gyrA were identified as key determinants of quinolone resistance in E. coli.
Prevalence, resistance mechanisms, and susceptibility of multidrug-resistant bloodstream isolates of Pseudomonas aeruginosa.
QRDR mutations, efflux system & antimicrobial resistance genes in enterotoxigenic Escherichia coli isolated from an outbreak of diarrhoea in Ahmedabad, India.
Plasmid-mediated quinolone resistance determinants in quinolone-resistant Escherichia coli isolated from patients with bacteremia in a university hospital in Taiwan, 2001-2015.
mutations in gyrA and parC were found in PMQR-harboring isolates
Mechanisms of quinolone resistance in Escherichia coli isolated from companion animals, pet-owners, and non-pet-owners.
Prevalence of plasmid-mediated quinolone resistance in Escherichia coli isolated from diseased animals in Taiwan.
Antimicrobial Resistance of Salmonella enterica Serovar Typhimurium in Shanghai, China.
Mutations in gyrA and parC genes contribute to ciprofloxacin resistance.
Genomic Serotyping, Clinical Manifestations, and Antimicrobial Resistance of Nontyphoidal Salmonella Gastroenteritis in Hospitalized Children in Ho Chi Minh City, Vietnam.
associated with ciprofloxacin resistance
Efflux Pump-Driven Antibiotic and Biocide Cross-Resistance in Pseudomonas aeruginosa Isolated from Different Ecological Niches: A Case Study in the Development of Multidrug Resistance in Environmental Hotspots.
mutations in gyrA contribute to fluoroquinolone resistance
Multiple Introductions of Salmonella enterica Serovar Typhi H58 with Reduced Fluoroquinolone Susceptibility into Chile.
Mutations in lineage II
Multidrug Resistant Klebsiella pneumoniae ST101 Clone Survival Chain From Inpatients to Hospital Effluent After Chlorine Treatment.
amino acid substitutions in GyrA
Whole-genome analyses of extended-spectrum or AmpC β-lactamase-producing Escherichia coli isolates from companion dogs in Japan.
associated with fluoroquinolone resistance
Escherichia coli Isolated from Diabetic Foot Osteomyelitis: Clonal Diversity, Resistance Profile, Virulence Potential, and Genome Adaptation.
Molecular Epidemiology and Clinical Characterization of Carbapenemase-Producing Enterobacter Species From an International Cohort.
Clonal Clusters, Molecular Resistance Mechanisms and Virulence Factors of Gram-Negative Bacteria Isolated from Chronic Wounds in Ghana.
Prevalence and Characterization of Quinolone-Resistance Determinants in Escherichia coli Isolated from Food-Producing Animals and Animal-Derived Food in the Philippines.
Mutations in bdcA and valS Correlate with Quinolone Resistance in Wastewater Escherichia coli.
known mutation
Genomic Epidemiology of Multidrug-Resistant Nontyphoidal Salmonella in Young Children Hospitalized for Gastroenteritis.
The genomic epidemiology of multi-drug resistant invasive non-typhoidal Salmonella in selected sub-Saharan African countries.
Mutations in gyrA confer resistance to fluoroquinolones.
Antimicrobial Resistance and Molecular Epidemiology of Uropathogenic Escherichia coli Isolated From Female Patients in Shanghai, China.
Genomic diversity of antimicrobial resistance in non-typhoidal Salmonella in Victoria, Australia.
Population snapshot of the extended-spectrum β-lactamase-producing Escherichia coli invasive strains isolated from a Hungarian hospital.
Genomic Profiling of Antibiotic-Resistant Escherichia coli Isolates from Surface Water of Agricultural Drainage in North-Western Mexico: Detection of the International High-Risk Lineages ST410 and ST617.
Double amino acid exchange in GyrA
Genetic and in-silico approaches for investigating the mechanisms of ciprofloxacin resistance in Salmonella typhi: Mutations, extrusion, and antimicrobial resistance.
Detection of the epidemic Pseudomonas aeruginosa AUST-03 (ST242) strain in people with cystic fibrosis in South Africa.
Genomic dynamics of high-risk carbapenem-resistant klebsiella pneumoniae clones carrying hypervirulence determinants in Egyptian clinical settings.
found in some isolates
Analysis of molecular mechanisms of delafloxacin resistance in Escherichia coli.
Mutations in QRDRs are associated with delafloxacin resistance
Genomic Characterization and Antimicrobial Resistance of ESBL-Producing, Escherichia coli Isolates in Suzhou, China.
Retrospective analysis of antimicrobial resistance associated with bovine respiratory disease.
The rise in domestic shigellosis and the genomic characteristics of Shigella clones linked to men who have sex with men in Taiwan, 2015‒2022.
Nalidixic acid-a good marker of fluoroquinolone resistance mechanisms in Escherichia coli.
Mechanisms of fluoroquinolone resistance among Escherichia coli isolates from urinary tract infections in Thailand.
Variants of β-lactamase-encoding genes are disseminated by multiple genetically distinct lineages of bloodstream Escherichia coli.
No evidence of multidrug-resistant Enterobacterales transmission between healthy companion animals and pet owners in the greater Atlanta area: a pilot study.
Gatifloxacin activity against quinolone-resistant gyrase: allele-specific enhancement of bacteriostatic and bactericidal activities by the C-8-methoxy group.
Single-nucleotide polymorphism mutation spectra and resistance to quinolones in Salmonella enterica serovar Enteritidis with a mutator phenotype.
Mutations in the quinolone resistance-determining region (QRDR) of gyrA were associated with resistance to quinolones.
Multidrug resistance in Salmonella enterica serotype Typhimurium from humans in France (1993 to 2003).
Application of an in vitro infection model and simulation for reevaluation of fluoroquinolone breakpoints for Salmonella enterica serotype typhi.
Mutations in gyrA contribute to fluoroquinolone resistance
Characterisation of Salmonella Enteritidis ST11 and ST1925 Associated with Human Intestinal and Extra-Intestinal Infections in Singapore.
Resistance mechanisms of multiresistant Pseudomonas aeruginosa strains from Germany and correlation with hypermutation.
Ciprofloxacin-resistant Salmonella enterica serotype Typhimurium, China.
Antimicrobial resistance, class 1 integrons, and genomic island 1 in Salmonella isolates from Vietnam.
Identification of an NDM-5-producing Escherichia coli Sequence Type 167 in a Neonatal Patient in China.
Contribution of target alteration, protection and efflux pump in achieving high ciprofloxacin resistance in Enterobacteriaceae.
Mutations in gyrA gene were identified in several Enterobacteriaceae isolates.
Mutation Supply and Relative Fitness Shape the Genotypes of Ciprofloxacin-Resistant Escherichia coli.
Whole-Genome Sequencing of Drug-Resistant Salmonella enterica Isolates from Dairy Cattle and Humans in New York and Washington States Reveals Source and Geographic Associations.
Mutations in gyrA are associated with quinolone resistance.
Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains.
Genomics and Susceptibility Profiles of Extensively Drug-Resistant Pseudomonas aeruginosa Isolates from Spain.
Phylogenetic and Evolutionary Analysis Reveals the Recent Dominance of Ciprofloxacin-Resistant Shigella sonnei and Local Persistence of S. flexneri Clones in India.
Mutations in gyr A contribute to fluoroquinolone resistance.
Epidemic characterization and molecular genotyping of Shigella flexneri isolated from calves with diarrhea in Northwest China.
Mutations in gyrA and parC contribute to fluoroquinolone resistance.
Characterization of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Isolates from Jurong Lake, Singapore with Whole-Genome-Sequencing.
Mutations in gyrA contribute to fluoroquinolone resistance.
Molecular characterization of fluoroquinolone-resistant Escherichia coli from broiler breeder farms.
Mutations in gyrA are associated with high-level fluoroquinolone resistance.
Emergence of mcr-1-Harboring Salmonella enterica Serovar Sinstorf Type ST155 Isolated From Patients With Diarrhea in Jiangsu, China.
Mutations in gyrA contribute to ciprofloxacin resistance.
Extensive Drug-Resistant Salmonella enterica Isolated From Poultry and Humans: Prevalence and Molecular Determinants Behind the Co-resistance to Ciprofloxacin and Tigecycline.
Mutations in gyrA gene were detected at codon S83 or D87 or both in 89.66% of XDR Salmonella.
Whole-Genome Sequencing of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli From Human Infections in Finland Revealed Isolates Belonging to Internationally Successful ST131-C1-M27 Subclade but Distinct From Non-human Sources.
Chromosomal quinolone resistance mutations in gyrA
Optimizing Nanopore Sequencing for Rapid Detection of Microbial Species and Antimicrobial Resistance in Patients at Risk of Surgical Site Infections.
Detected in Salmonella enterica
Whole Genome Sequence Analysis of Multidrug Resistant Escherichia coli and Klebsiella pneumoniae Strains in Kuwait.
Global population structure of the Serratia marcescens complex and identification of hospital-adapted lineages in the complex.
Genomics of human and chicken Salmonella isolates in Senegal: Broilers as a source of antimicrobial resistance and potentially invasive nontyphoidal salmonellosis infections.
Research note: The resistome of commensal Escherichia coli isolated from broiler carcasses "produced without the use of antibiotics"(a).
Virulome and genome analyses identify associations between antimicrobial resistance genes and virulence factors in highly drug-resistant Escherichia coli isolated from veal calves.
Genomic perspective on the bacillus causing paratyphoid B fever.
Mutations in quinolone resistance-determining regions of gyrA and gyrB
Fluoroquinolone-specific resistance trajectories in E. coli and their dependence on the SOS-response.
Wastewater based genomic surveillance key to population level monitoring of AmpC/ESBL producing Escherichia coli.
Prevalence and characterization of ciprofloxacin-resistant Salmonella enterica spp. isolated from food animals during 2010-2023 in South Korea.
Genomic analyses reveal presence of extensively drug-resistant Salmonella enterica serovars isolated from clinical samples in Guizhou province, China, 2019-2023.
Mutations in quinolone resistance-determining regions (QRDRs)
Genomic insights into antimicrobial resistance and virulence of E. coli in central Ethiopia: a one health approach.
Fluoroquinolone resistance in complicated urinary tract infections: association with the increased occurrence and diversity of Escherichia coli of clonal complex 131, together with ST1193.
Mutations associated with fluoroquinolone resistance
Exploring the potential role of GyrA inhibiting quinoline analog: an in silico study.
All mutations are in the quinolone resistance-determining region (QRDR) of gyrA.
Analyzing Shigella in Wuhan: Serotypes, Antimicrobial Resistance, and Public Health Implications.
Plasmid-driven clonal expansion of multidrug-resistant monophasic Salmonella Typhimurium in a Global Food Trade Hub.
Genomic evolution of Salmonella Dublin in cattle and humans in the United States.
Characteristics of quinolone resistance in Escherichia coli isolated from wildlife in Poland.
Mutations in QRDR region are associated with high MIC values
Genomic and epidemiological characteristics of Shigella boydii in Australia, 1991-2022.
A contemporary genomic snapshot of Salmonella Paratyphi A in Pakistan.
Multiple point mutations in gyrA were identified, contributing to ciprofloxacin resistance.
Molecular characterization of mcr-1.1-harboring multidrug-resistant Escherichia coli isolates from chicken in the United Arab Emirates: implications for one health surveillance.
Mutations in gyrA contribute to fluoroquinolone resistance
Trends in serotype distribution and antimicrobial susceptibility in Salmonella enterica isolates from humans in Belgium, 2009 to 2013.
Genomic signature of multidrug-resistant Salmonella enterica serovar typhi isolates related to a massive outbreak in Zambia between 2010 and 2012.
High resolution melting analysis for rapid mutation screening in gyrase and Topoisomerase IV genes in quinolone-resistant Salmonella enterica.
missense mutation
In vivo selection of resistant E. coli after ingestion of milk with added drug residues.
Comparative analysis of quinolone resistance in clinical isolates of Klebsiella pneumoniae and Escherichia coli from Chinese children and adults.
Enhanced resistance to fluoroquinolones in laboratory-grown mutants & clinical isolates of Shigella due to synergism between efflux pump expression & mutations in quinolone resistance determining region.
Mutations in QRDR of gyrA contribute to fluoroquinolone resistance
Antimicrobial resistance and management of invasive Salmonella disease.
Antimicrobial susceptibility of travel-related Salmonella enterica serovar Typhi isolates detected in Switzerland (2002-2013) and molecular characterization of quinolone resistant isolates.
'Supermutators' found amongst highly levofloxacin-resistant E. coli isolates: a rapid protocol for the detection of mutation sites.
The gyrA-R237H mutation was strongly associated with HR isolates.
Genomic epidemiology reveals geographical clustering of multidrug-resistant Escherichia coli ST131 associated with bacteraemia in Wales.
Phenotypic and genetic characterization of antimicrobial resistance in Salmonella enterica serovar Choleraesuis isolates from humans and animals in Spain from 2006 to 2021.
Polymyxin Resistance in Salmonella: Exploring Mutations and Genetic Determinants of Non-Human Isolates.
Prevalence and molecular characterization of multi-resistant Escherichia coli isolates from clinical bovine mastitis in China.
Investigation of Nalidixic Acid Resistance Mechanism in Salmonella enterica Using Molecular Simulation Techniques.
Increasing prevalence of ciprofloxacin-resistant food-borne Salmonella strains harboring multiple PMQR elements but not target gene mutations.
Single or double mutations in gyrA and/or parC
Emergence and Diversity of Salmonella enterica Serovar Indiana Isolates with Concurrent Resistance to Ciprofloxacin and Cefotaxime from Patients and Food-Producing Animals in China.
Shigella Antimicrobial Drug Resistance Mechanisms, 2004-2014.
mutations in gyrA are associated with fluoroquinolone resistance
S. Enteritidis and S. Typhimurium Harboring SPI-1 and SPI-2 Are the Predominant Serotypes Associated With Human Salmonellosis in Saudi Arabia.
Analysis of isolates from Bangladesh highlights multiple ways to carry resistance genes in Salmonella Typhi.
Mutations in gyrA are associated with ciprofloxacin resistance.
Pandemic fluoroquinolone resistant Escherichia coli clone ST1193 emerged via simultaneous homologous recombinations in 11 gene loci.
Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000-2016.
Informal genomic surveillance of regional distribution of Salmonella Typhi genotypes and antimicrobial resistance via returning travellers.
Mutations in the quinolone resistance determining region (QRDR) of gyrA and parC are associated with reduced susceptibility to fluoroquinolones.
Persistent circulation of a fluoroquinolone-resistant Salmonella enterica Typhi clone in the Indian subcontinent.
Mutations in gyrA and parC contribute to fluoroquinolone resistance.
The Resistome, Mobilome, Virulome and Phylogenomics of Multidrug-Resistant Escherichia coli Clinical Isolates from Pretoria, South Africa.
Mutations in gyrA contribute to fluoroquinolone resistance.
Impact of co-existence of PMQR genes and QRDR mutations on fluoroquinolones resistance in Enterobacteriaceae strains isolated from community and hospital acquired UTIs.
Diversity of Serotype, Genotype, and Antibiotic Susceptibility of Salmonella Prevalent in Pickled Ready-to-Eat Meat.
Mutations in GyrA are associated with fluoroquinolone resistance.
Mutations in GyrA contribute to quinolone resistance.
Ciprofloxacin-Resistant Salmonella enterica Serovar Kentucky ST198 in Broiler Chicken Supply Chain and Patients, China, 2010-2016.
Mutations in gyrA contribute to nalidixic acid resistance.
International lineages of Salmonella enterica serovars isolated from chicken farms, Wakiso District, Uganda.
Occurrence and molecular characteristics of antimicrobial resistance, virulence factors, and extended-spectrum β-lactamase (ESBL) producing Salmonella enterica and Escherichia coli isolated from the retail produce commodities in Bangkok, Thailand.
Found in S. enterica isolate SE01
Genomic Characterization of a Plasmid-Free and Highly Drug-Resistant Salmonella enterica Serovar Indiana Isolate in China.
A novel variant in Salmonella genomic island 1 of multidrug-resistant Salmonella enterica serovar Kentucky ST198.
Mutations in the quinolone resistance-determining region (QRDR) of gyrA.
Development of an in vitro biofilm model for the study of the impact of fluoroquinolones on sewer biofilm microbiota.
Antimicrobial resistance and population genomics of emerging multidrug-resistant Salmonella 4,[5],12:i:- in Guangdong, China.
Multiplex Real-Time Polymerase Chain Reaction-Based Method for the Rapid Detection of gyrA and parC Mutations in Quinolone-Resistant Escherichia coli and Shigella spp.
The global establishment of a highly-fluoroquinolone resistant Salmonella enterica serotype Kentucky ST198 strain.
associated with ciprofloxacin resistance
Lack of efflux mediated quinolone resistance in Salmonella enterica serovars Typhi and Paratyphi A.
associated with resistance
Emergence of clinical Salmonella enterica serovar Typhimurium isolates with concurrent resistance to ciprofloxacin, ceftriaxone, and azithromycin.
Quinolone resistance mechanisms among extended-spectrum beta-lactamase (ESBL) producing Escherichia coli isolated from rivers and lakes in Switzerland.
Fluoroquinolone resistance mechanisms of Shigella flexneri isolated in Bangladesh.
Mutations in gyrA contribute to fluoroquinolone resistance
Antimicrobial resistance in Salmonella enterica Serovar Typhi isolates from Bangladesh, Indonesia, Taiwan, and Vietnam.
Mutations in gyrA and parC contribute to quinolone resistance.
Fluoroquinolone resistance in Salmonella: insights by whole-genome sequencing.
chromosomal mutations in gyrA contribute to fluoroquinolone resistance
Variant O89 O-Antigen of E. coli Is Associated With Group 1 Capsule Loci and Multidrug Resistance.
Mutations in gyrA contribute to quinolone resistance.
A systematic review of antimicrobial resistance in Salmonella enterica serovar Typhi, the etiological agent of typhoid.
Multidrug resistant Pseudomonas aeruginosa in Estonian hospitals.
Salmonella enterica Serovar Typhi in Bangladesh: Exploration of Genomic Diversity and Antimicrobial Resistance.
Mutations in gyrA are associated with ciprofloxacin resistance.
Molecular characterisation of the NDM-1-encoding plasmid p2189-NDM in an Escherichia coli ST410 clinical isolate from Ghana.
Evaluation of co-transfer of plasmid-mediated fluoroquinolone resistance genes and bla(NDM) gene in Enterobacteriaceae causing neonatal septicaemia.
Mutations in gyrA contribute to fluoroquinolone resistance.
Association of fluoroquinolone resistance, virulence genes, and IncF plasmids with extended-spectrum-β-lactamase-producing Escherichia coli sequence type 131 (ST131) and ST405 clonal groups.
Effects of a previously selected antibiotic resistance on mutations acquired during development of a second resistance in Escherichia coli.
Mutations in gyrA were observed in wild-type E. coli adapted to enrofloxacin.
Non-typhoidal Salmonella blood stream infection in Kuwait: Clinical and microbiological characteristics.
Mutations in gyrA gene confer resistance to ciprofloxacin.
Genomic Investigation of the Emergence of Invasive Multidrug-Resistant Salmonella enterica Serovar Dublin in Humans and Animals in Canada.
Mutations in gyrA lead to fluoroquinolone resistance.
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.
Chromosomally and Plasmid-Located mcr in Salmonella from Animals and Food Products in China.
Antimicrobial resistance and genomic characterization of Salmonella enterica serovar Senftenberg isolates in production animals from the United States.
Detection and characterization of ESBL-producing Escherichia coli and additional co-existence with mcr genes from river water in northern Thailand.
Increases in the Macrolide Resistance of Mycoplasma genitalium and the Emergence of the A2058T Mutation in the 23S rRNA Gene: Clonal Spread?
mutation in gyrA gene
Genetic Predictive Factors for Nonsusceptible Phenotypes and Multidrug Resistance in Expanded-Spectrum Cephalosporin-Resistant Uropathogenic Escherichia coli from a Multicenter Cohort: Insights into the Phenotypic and Genetic Basis of Coresistance.
Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds.
Study on the drug resistance and pathogenicity of Escherichia coli isolated from calf diarrhea and the distribution of virulence genes and antimicrobial resistance genes.
One health clones of multidrug-resistant Escherichia coli carried by synanthropic animals in Brazil.
An ST131 clade and a phylogroup A clade bearing an O101-like O-antigen cluster predominate among bloodstream Escherichia coli isolates from South-West Nigeria hospitals.
Mutations in gyrA contribute to fluoroquinolone resistance.
Role of the Water-Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase.
Wild-type GyrA is susceptible to quinolones
Quinolone-resistant Escherichia coli at the interface between humans, poultry and their shared environment- a potential public health risk.
Single substitution
Carbapenem-Resistant and ESBL-Producing Enterobacterales Emerging in Central Texas.
Mutations in gyrA contribute to fluoroquinolone resistance.
Whole-Genome Analysis of Antimicrobial-Resistant Salmonella enterica Isolated from Duck Carcasses in Hanoi, Vietnam.
Discovery of a novel sub-lineage of multi-drug resistant Shigella flexneri in Southern California.
chromosomal mutation
Genome profiling of uropathogenic E. coli from strictly defined community-acquired UTI in paediatric patients: a multicentric study.
Characterization of cephalosporin and fluoroquinolone resistant Enterobacterales from Irish farm waste by whole genome sequencing.
Genetic characterization of ESBL-producing and ciprofloxacin-resistant Escherichia coli from Belgian broilers and pigs.
Mutations in QRDR of gyrA and parC were found in all ciproR-E. coli.
Genomic Characterization of Uropathogenic Escherichia coli Isolates from Tertiary Hospitals in Riyadh, Saudi Arabia.
Genomic Characterization and Genetic Profiles of Salmonella Gallinarum Strains Isolated from Layers with Fowl Typhoid in Colombia.
Multidrug-resistant non-typhoidal Salmonella of public health significance recovered from migratory birds in Bangladesh.
Uropathogenic Escherichia coli population structure and antimicrobial susceptibility in Norfolk, UK.
Mechanisms of reduced susceptibility to ciprofloxacin in Escherichia coli isolates from Canadian hospitals.
Incidence and Genomic Background of Antibiotic Resistance in Food-Borne and Clinical Isolates of Salmonella enterica Serovar Derby from Spain.
Point mutation in the gyrA gene associated with nalidixic acid resistance.
Genomic Characterization of Salmonella Isangi: A Global Perspective of a Rare Serovar.
Salmonella isangi gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3007751
Founding of the culture collection of antibiotic-resistant strains of zoonotic bacteria in the Russian Federation.
High Levels of Antibiotic Resistance in MDR-Strong Biofilm-Forming Salmonella Typhimurium ST34 in Southern China.
Genomic analysis and antimicrobial activity of β-lactam/β-lactamase inhibitors and other agents against KPC-producing Klebsiella pneumoniae clinical isolates from Brazilian hospitals.
Phenotypic and genotypic antimicrobial resistance correlation and plasmid characterization in Salmonella spp. isolates from Italy reveal high heterogeneity among serovars.
Chance Favors the Prepared Genomes: Horizontal Transfer Shapes the Emergence of Antibiotic Resistance Mutations in Core Genes.
One of the most frequent mutations in E. coli
The clinical, genomic, and microbiological profile of invasive multi-drug resistant Escherichia coli in a major teaching hospital in the United Kingdom.
Mutations in gyrA contribute to ciprofloxacin resistance.
Fluoroquinolone resistance determinants in carbapenem-resistant Escherichia coli isolated from urine clinical samples in Thailand.
most common mutation
Molecular epidemiology and pathogenomics of extended-spectrum beta-lactamase producing- Escherichia coli and - Klebsiella pneumoniae isolates from bulk tank milk in Tennessee, USA.
Mutations in gyrA contribute to fluoroquinolone resistance.
Emergence and persistent spread of carbapenemase-producing Klebsiella pneumoniae high-risk clones in Greek hospitals, 2013 to 2022.
Distribution of Extended-Spectrum-β-Lactamase-Producing Diarrheagenic Escherichia coli Clonal Complex 10 Isolates from Patients with Diarrhea in the Republic of Korea.
Escherichia coli sequence type 410 with carbapenemases: a paradigm shift within E. coli toward multidrug resistance.
associated with fluoroquinolone resistance
Genotypic Characterization of Uropathogenic Escherichia coli from Companion Animals: Predominance of ST372 in Dogs and Human-Related ST73 in Cats.
Frequency and factors associated with carriage of multi-drug resistant commensal Escherichia coli among women attending antenatal clinics in central India.
Mutations in the quinolone resistance-determining regions of gyrA and parC in Enterobacteriaceae isolates from Brazil.
Multiple mutations in gyrA and parC genes are associated with high-level fluoroquinolone resistance.
Presence of multi-drug resistant pathogenic Escherichia coli in the San Pedro River located in the State of Aguascalientes, Mexico.
Mutations in the quinolone-resistance determining regions of gyrA and parC genes
Characterization and comparison of extended-spectrum β-lactamase (ESBL) resistance genotypes and population structure of Escherichia coli isolated from Franklin's gulls (Leucophaeus pipixcan) and humans in Chile.
Mutations in gyrA were found in avian ESBL isolates.
Emergence of Resistance Mutations in Salmonella enterica Serovar Typhi Against Fluoroquinolones.
Mutations in gyrA contribute to fluoroquinolone resistance
Analytical profiling of mutations in quinolone resistance determining region of gyrA gene among UPEC.
Mutations in the QRDR of gyrA are strongly associated with quinolone resistance in UPEC.
Fitness Tradeoffs of Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli.
Overview of the development of quinolone resistance in Salmonella species in China, 2005-2016.
mutations in QRDRs of gyrA are associated with reduced CIP susceptibility
Out of Asia: the independent rise and global spread of fluoroquinolone-resistant Shigella.
mutations in QRDR region of gyrA and parC are primarily responsible for fluoroquinolone resistance in Shigella
Laboratory and molecular surveillance of paediatric typhoidal Salmonella in Nepal: Antimicrobial resistance and implications for vaccine policy.
Mutations in the QRDR of gyrA contribute to fluoroquinolone resistance.
Complete Genomic Analysis of a Salmonella enterica Serovar Typhimurium Isolate Cultured From Ready-to-Eat Pork in China Carrying One Large Plasmid Containing mcr-1.
Pathogenic potential and the role of clones and plasmids in beta-lactamase-producing E. coli from chicken faeces in Vietnam.
Mutations in the quinolone resistance-determining region (QRDR) of gyrA and parC genes.
Phylogenetic Analysis Indicates a Longer Term Presence of the Globally Distributed H58 Haplotype of Salmonella Typhi in Southern India.
Machine learning with random subspace ensembles identifies antimicrobial resistance determinants from pan-genomes of three pathogens.
Mutations in gyrA and parC are associated with fluoroquinolone resistance in various bacterial species.
Population structure and antimicrobial resistance patterns of Salmonella Typhi isolates in urban Dhaka, Bangladesh from 2004 to 2016.
Exploring the success of Brazilian endemic clone Pseudomonas aeruginosa ST277 and its association with the CRISPR-Cas system type I-C.
Antimicrobial resistance and novel mutations detected in the gyrA and parC genes of Pseudomonas aeruginosa strains isolated from companion dogs.
Mutations in gyrA were significantly more common in strains from the infected group than in those from the healthy group
Genomic profiling of antimicrobial resistance genes in clinical isolates of Salmonella Typhi from patients infected with Typhoid fever in India.
Predictable properties of fitness landscapes induced by adaptational tradeoffs.
Persistent Asymptomatic Human Infections by Salmonella enterica Serovar Newport in China.
Found in four strains isolated from diarrheic patients.
Characterizing Antimicrobial Resistant Escherichia coli and Associated Risk Factors in a Cross-Sectional Study of Pig Farms in Great Britain.
Title of the Paper
recessive mutation
Molecular characteristics of fluoroquinolone-resistant avian pathogenic Escherichia coli isolated from broiler chickens.
The prevalence and mechanism of fluoroquinolone resistance in Escherichia coli isolated from swine farms in China.
Mutations in the QRDR region
Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa.
mutations in gyrA contribute to fluoroquinolone resistance in P. aeruginosa
Profiles of gyrA Mutations and Plasmid-Mediated Quinolone Resistance Genes in Shigella Isolates with Different Levels of Fluoroquinolone Susceptibility.
Present in ciprofloxacin-intermediate and ciprofloxacin-resistant isolates.
Whole genome sequencing analyses revealed that Salmonella enterica serovar Dublin strains from Brazil belonged to two predominant clades.
Spread of Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates Producing NDM-Type Metallo-β-Lactamase in Myanmar.
Dynamics of Antimicrobial Resistance and Genomic Epidemiology of Multidrug-Resistant Salmonella enterica Serovar Indiana ST17 from 2006 to 2017 in China.
Mutations in gyrA contribute to fluoroquinolone resistance.
Genome Analysis of ESBL-Producing Escherichia coli Isolated from Pigs.
Antimicrobial resistance genes, virulence markers and prophage sequences in Salmonella enterica serovar Enteritidis isolated in Tunisia using whole genome sequencing.
Mutations in gyrA gene confer resistance to nalidixic acid and pefloxacin.
Genomic surveillance of Salmonella spp. in the Philippines during 2013-2014.
Molecular characterization of circulating Salmonella Typhi strains in an urban informal settlement in Kenya.
Prevalence of Plasmid-Mediated Quinolone Resistance (PMQRs) Determinants and Whole Genome Sequence Screening of PMQR-Producing E. coli Isolated from Men Undergoing a Transrectal Prostate Biopsy.
Molecular Evolution of the Pseudomonas aeruginosa DNA Gyrase gyrA Gene.
Mutations in gyrA are associated with quinolone resistance
Molecular characteristics of fluoroquinolone-resistant Escherichia coli isolated from suckling piglets with colibacillosis.
Antimicrobial resistance of Salmonella Indiana from retail chickens in China and emergence of an mcr-1-harboring isolate with concurrent resistance to ciprofloxacin, cefotaxime, and colistin.
Whole-Genome Sequence Analysis of Antibiotic Resistance, Virulence, and Plasmid Dynamics in Multidrug-Resistant E. coli Isolates from Imported Shrimp.
Genome Sequences of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Recovered from Mid-Stream Urine Samples in Accra, Ghana.
Systematic in vitro optimization of antimicrobial peptides against Escherichia coli.
The Prevalence of Multidrug-Resistant Escherichia coli in Chennai and Whole Genome Sequence Analysis of Carbapenem-Resistant Escherichia coli ST410.
Comparative genomics of quinolone-resistant Escherichia coli from broilers and humans in Norway.
Investigation of gyrA and parC mutations and the prevalence of plasmid-mediated quinolone resistance genes in Klebsiella pneumoniae clinical isolates.
Characterization of a Salmonella enterica serovar Typhimurium lineage with rough colony morphology and multidrug resistance.
Global genomic diversity of Pseudomonas aeruginosa in bronchiectasis.
Mutations in gyrA lead to fluoroquinolone resistance
Comparative in vitro activity of Delafloxacin and other antimicrobials against isolates from patients with acute bacterial skin, skin-structure infection and osteomyelitis.
Genome-Based Analysis of Genetic Diversity, Antimicrobial Susceptibility, and Virulence Gene Distribution in Salmonella Pullorum Isolates from Poultry in China.
Monitoring of Pseudomonas aeruginosa mutational resistome dynamics using an enrichment panel for direct sequencing of clinical samples.
Detected in ST175 isolate.
gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae.
gyrA
Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals.
gyrA
Association between double mutation in gyrA gene of ciprofloxacin-resistant clinical isolates of Escherichia coli and MICs.
gyrA
Escherichia coli gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003294
Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.
gyrA
Susceptibility patterns of enteroaggregative Escherichia coli associated with traveller's diarrhoea: emergence of quinolone resistance.
gyrA
DNA gyrase gyrA mutations in quinolone-resistant clinical isolates of Pseudomonas aeruginosa.
gyrA
Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003684
Mechanisms of quinolone resistance in Escherichia coli and Salmonella: recent developments.
gyrA
Accumulation of mutations in DNA gyrase and topoisomerase IV genes contributes to fluoroquinolone resistance in Vibrio cholerae O139 strains.
gyrA
Characterisation of novel mutations involved in quinolone resistance in Escherichia coli isolated from imported shrimp.
Escherichia coli gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003294
Prevalence of gyrA Mutations in Nalidixic Acid-Resistant Strains of Salmonella Enteritidis Isolated from Humans, Food, Chickens, and the Farm Environment in Brazil.
Salmonella enterica gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003926
Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals.
D87G or D87Y confer resistance to nalidixic acid only, if occurring alone. Unknown phenotype if D87H occurs alone
4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction.
D87G or D87Y confer resistance to nalidixic acid only, if occurring alone. Unknown phenotype if D87H occurs alone
Detection of mutations in the gyrA and parC genes in Escherichia coli isolates carrying plasmid-mediated quinolone resistance genes from diseased food-producing animals.
D87G or D87Y confer resistance to nalidixic acid only, if occurring alone. Unknown phenotype if D87H occurs alone
High prevalence of acquired quinolone-resistance genes among Enterobacteriaceae from Saudi Arabia with CTX-M-15 β-lactamase.
Under development. Phenotype should be used with caution.
Comparative studies of mutations in animal isolates and experimental in vitro- and in vivo-selected mutants of Salmonella spp. suggest a counterselection of highly fluoroquinolone-resistant strains in the field.
[Resistance to quinolones and beta-lactams in Salmonella enterica due to mutations in topoisomerase-encoding genes, altered cell permeability and expression of an active efflux system].
Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance.
A multiplex single nucleotide polymorphism typing assay for detecting mutations that result in decreased fluoroquinolone susceptibility in Salmonella enterica serovars Typhi and Paratyphi A.
Mutations in gyrA are associated with decreased fluoroquinolone susceptibility.
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