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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations alrD322N

Genealr

Alanine racemase

Protein ChangeD322N

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: decreased affinity for DCS
Resistance To: D-cycloserine
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes.

PMID 31519879 · 2019

mutations in the alr gene contribute to DCS resistance

Mutation Information

Protein Change: D322N
Organisms: Mycobacterium tuberculosis
Confers Resistance To: D-cycloserine

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

decreased affinity for DCS

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research