Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
A computational perspective on the dynamic behaviour of recurrent drug resistance mutations in the pncA gene from Mycobacterium tuberculosis.
Mutations in the pncA gene lead to reduced binding affinity of PZA to PZase, resulting in pyrazinamide resistance.
pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia.
Mutations in the pncA gene are associated with pyrazinamide resistance in Mycobacterium tuberculosis.
A Novel Molecular Strategy for Surveillance of Multidrug Resistant Tuberculosis in High Burden Settings.
Mutations in pncA are associated with pyrazinamide resistance.
A retrospective genomic analysis of drug-resistant strains of M. tuberculosis in a high-burden setting, with an emphasis on comparative diagnostics and reactivation and reinfection status.
Overcoming the pitfalls of automatic interpretation of whole genome sequencing data by online tools for the prediction of pyrazinamide resistance in Mycobacterium tuberculosis.
Mutations in pncA were associated with pyrazinamide resistance.
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics.
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394
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