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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations mmpR5R90C

transcriptional repressor of the MmpS5-MmpL5 efflux pump

Protein ChangeR90C

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss of function
Resistance To: Bedaquiline
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Detection of a historic reservoir of bedaquiline/clofazimine resistance-associated variants in Mycobacterium tuberculosis.

PMID 38374151 · 2024

Mutations in mmpR5 affecting bedaquiline resistance

Mutation Information

Protein Change: R90C
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Bedaquiline

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

loss of function

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research