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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations gyrAD81N

GenegyrA

Protein ChangeD81N

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene CatalogReslit

Overview

Mechanism: DNA gyrase subunit A GyrA, single resistance variant
Resistance To: Enrofloxacin, QUINOLONE, Fluoroquinolones
Organisms: Mycoplasma agalactiae, Clostridioides difficile
Papers: 2

Paper Information2

1

Mycoplasmas under experimental antimicrobial selection: The unpredicted contribution of horizontal chromosomal transfer.

PMID 30668569 · 2019

Mutation Information

Protein Change: D81N
Organisms: Mycoplasma agalactiae
Confers Resistance To: Enrofloxacin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Source Database

Reslit

2

Characterizations of clinical isolates of clostridium difficile by toxin genotypes and by susceptibility to 12 antimicrobial agents, including fidaxomicin (OPT-80) and rifaximin: a multicenter study in Taiwan.

PMID 22508299 · 2012

gyrA

Clostridioides difficile gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003995

Mutation Information

Protein Change: D81N
Organisms: Clostridioides difficile
Confers Resistance To: QUINOLONEFluoroquinolones
Effect on Function: DNA gyrase subunit A GyrA; single resistance variant
Source Database: Reference Gene CatalogCard Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research