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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations gyrAGAT->ATT

GenegyrA

Nucleotide ChangeGAT->ATT

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Overview

Resistance To: Fluoroquinolones
Organisms: E. coli
Papers: 2

Paper Information2

1

Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase.

PMID 28507124 · 2017

Mutations in gyrA confer resistance to fluoroquinolones

Mutation Information

gyrA: p.S83I / c.GAT->ATT

Protein Change: S83I
Nucleotide Change: GAT->ATT
Organisms: E. coli
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Fluoroquinolones

Source Database

Reslit

2

Nanopore-only assemblies for genomic surveillance of the global priority drug-resistant pathogen, Klebsiella pneumoniae.

PMID 36752781 · 2023

Mutation Information

gyrA: c.GAT->ATT

Nucleotide Change: GAT->ATT
Confers Resistance To: Fluoroquinolones
Source Database: Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research