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Browse Mutations rpoBH451L

GenerpoB

Protein ChangeH451L

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Investigation of Multi-Subunit Mycobacterium tuberculosis DNA-Directed RNA Polymerase and Its Rifampicin Resistant Mutants.

PMID 36834726 · 2023

All mutations are located in the RIF-resistance-determining region (RRDR) of rpoB.

Mutation Information

Protein Change: H451L
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Rifampicin
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research